Recombinant Human sFRP-1 (Histidine-tagged) Protein | R&D Systems 1384-SF-025 product information

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Human sFRP-1 (Histidine-tagged) Protein

catalog :

1384-SF-025

quantity :

25 ug

price :

396 USD

more info or order :

R&D Systems product webpage

citations: 8

Reference
Skaria T, Bächli E, Schoedon G. WIF1 prevents Wnt5A mediated LIMK/CFL phosphorylation and adherens junction disruption in human vascular endothelial cells. J Inflamm (Lond). 2017;14:10 pubmed publisher
Skaria T, Bächli E, Schoedon G. Wnt5A/Ryk signaling critically affects barrier function in human vascular endothelial cells. Cell Adh Migr. 2017;11:24-38 pubmed publisher
Shen X, Ying H, Yue B. Wnt activation by wild type and mutant myocilin in cultured human trabecular meshwork cells. PLoS ONE. 2012;7:e44902 pubmed publisher
Gogolla N, Galimberti I, Deguchi Y, Caroni P. Wnt signaling mediates experience-related regulation of synapse numbers and mossy fiber connectivities in the adult hippocampus. Neuron. 2009;62:510-25 pubmed publisher
Kobune M, Kawano Y, Takahashi S, Takada K, Murase K, Iyama S, et al. Interaction with human stromal cells enhances CXCR4 expression and engraftment of cord blood Lin(-)CD34(-) cells. Exp Hematol. 2008;36:1121-31 pubmed publisher
Lane N, Nevitt M, Lui L, de Leon P, Corr M. Wnt signaling antagonists are potential prognostic biomarkers for the progression of radiographic hip osteoarthritis in elderly Caucasian women. Arthritis Rheum. 2007;56:3319-25 pubmed
Wawrzak D, Metioui M, Willems E, Hendrickx M, De Genst E, Leyns L. Wnt3a binds to several sFRPs in the nanomolar range. Biochem Biophys Res Commun. 2007;357:1119-23 pubmed
Lindsley R, Gill J, Kyba M, Murphy T, Murphy K. Canonical Wnt signaling is required for development of embryonic stem cell-derived mesoderm. Development. 2006;133:3787-96 pubmed

product information

brand :

R&D Systems, a Bio-Techne Brand

catalog number base :

1384-SF

SKU :

1384-SF-025

product name :

Recombinant Human sFRP-1 (Histidine-tagged) Protein

Description :

The Recombinant Human sFRP-1 (Histidine-tagged) Protein from R&D Systems is derived from NS0. The Recombinant Human sFRP-1 (Histidine-tagged) Protein has been validated for the following applications: Bioactivity.

target :

sFRP-1

category :

Proteins and Enzymes

unit size :

25 ug

buffer :

Lyophilized from a 0.2 µm filtered solution in NaH2PO4 and NaCl with BSA as a carrier protein.

conjugate :

Unconjugated

purity :

>95%, by SDS-PAGE under reducing conditions and visualized by silver stain.

species :

Human

observed molecular weight :

35-40 kDa, reducing conditions

theoretical molecular weight :

33 kDa

gene symbol :

SFRP1

details of functionality :

Measured by its ability to inhibit proliferation of HeLa human cervical epithelial carcinoma cells. Ko, L. et al . (2002) Exp. Cell Res. 280 :280. The ED50 for this effect is 2.5-10 µg/mL.

endotoxin note :

<0.10 EU per 1 µg of the protein by the LAL method.

accessionNumbers :

AAB70793

applications :

Bioactivity

source :

NS0-derived Recombinant Human sFRP-1 (Histidine-tagged) Protein

USD :

396 USD

alt names :

FRP1, FRP-1FrzA, FRPSARP-2, FrzA, SARP-2, SARP2sFRP-1, Secreted apoptosis-related protein 2, secreted frizzled-related protein 1, sFRP1

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage