Recombinant Human ULBP-1 Fc Chimera Protein, CF | R&D Systems 1380-UL-050 product information

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Human ULBP-1 Fc Chimera Protein, CF

catalog :

1380-UL-050

quantity :

50 ug (also 1 mg)

price :

423 USD

more info or order :

R&D Systems product webpage

citations: 6

Reference
Weil S, Memmer S, Lechner A, Huppert V, Giannattasio A, Becker T, et al. Natural Killer Group 2D Ligand Depletion Reconstitutes Natural Killer Cell Immunosurveillance of Head and Neck Squamous Cell Carcinoma. Front Immunol. 2017;8:387 pubmed publisher
Raneros A, Puras A, Rodriguez R, Colado E, Bernal T, Anguita E, et al. Increasing TIMP3 expression by hypomethylating agents diminishes soluble MICA, MICB and ULBP2 shedding in acute myeloid leukemia, facilitating NK cell-mediated immune recognition. Oncotarget. 2017;8:31959-31976 pubmed publisher
Ibusuki A, Kawai K, Yoshida S, Uchida Y, Nitahara Takeuchi A, Kuroki K, et al. NKG2D triggers cytotoxicity in murine epidermal ?? T cells via PI3K-dependent, Syk/ZAP70-independent signaling pathway. J Invest Dermatol. 2014;134:396-404 pubmed publisher
Nuckel H, Switala M, Sellmann L, Horn P, Durig J, Duhrsen U, et al. The prognostic significance of soluble NKG2D ligands in B-cell chronic lymphocytic leukemia. Leukemia. 2010;24:1152-9 pubmed publisher
Ho V, Vanneman M, Kim H, Sasada T, Kang Y, Pasek M, et al. Biologic activity of irradiated, autologous, GM-CSF-secreting leukemia cell vaccines early after allogeneic stem cell transplantation. Proc Natl Acad Sci U S A. 2009;106:15825-30 pubmed publisher
Diermayr S, Himmelreich H, Durovic B, Mathys Schneeberger A, Siegler U, Langenkamp U, et al. NKG2D ligand expression in AML increases in response to HDAC inhibitor valproic acid and contributes to allorecognition by NK-cell lines with single KIR-HLA class I specificities. Blood. 2008;111:1428-36 pubmed

product information

brand :

R&D Systems, a Bio-Techne Brand

catalog number base :

1380-UL

SKU :

1380-UL-050

product name :

Recombinant Human ULBP-1 Fc Chimera Protein, CF

Description :

The Recombinant Human ULBP-1 Fc Chimera Protein, CF from R&D Systems is derived from Sf 21 (stably transfected). The Recombinant Human ULBP-1 Fc Chimera Protein, CF has been validated for the following applications: Binding Activity.

target :

ULBP-1

category :

Proteins and Enzymes

unit size :

50 ug (also 1 mg)

buffer :

Lyophilized from a 0.2 µm filtered solution in PBS.

conjugate :

Unconjugated

purity :

>90%, by SDS-PAGE under reducing conditions and visualized by silver stain

species :

Human

observed molecular weight :

55 kDa, reducing conditions

theoretical molecular weight :

48.8 kDa (monomer)

gene symbol :

ULBP1

details of functionality :

Measured by its ability to bind rhNKG2D/Fc Chimera in a functional ELISA.

endotoxin note :

<0.10 EU per 1 µg of the protein by the LAL method.

accessionNumbers :

Q9BZM6

applications :

Binding Activity

source :

Sf 21 (stably transfected)-derived Recombinant Human ULBP-1 Fc Chimera Protein

USD :

423 USD

alt names :

ALCAN-beta, MULT-1, N2DL1, N2DL-1, NKG2D ligand 1, NKG2DL, NKG2DL1, RAET1I, RAET1Ialcan-beta, Retinoic acid early transcript 1I, UL16 binding protein 1, UL16-binding protein 1, ULBP1

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage