product summary
Loading...
company name :
R&D Systems
product type :
protein
product name :
Recombinant Human Granzyme H Protein, CF
catalog :
1377-SE-010
quantity :
10 ug
price :
456 USD
more info or order :
citations: 2
Reference |
---|
Fellows E, Gil Parrado S, Jenne D, Kurschus F. Natural killer cell-derived human granzyme H induces an alternative, caspase-independent cell-death program. Blood. 2007;110:544-52 pubmed
|
product information
master code :
1377-SE
SKU :
1377-SE-010
product name :
Recombinant Human Granzyme H Protein, CF
unit size :
10 ug
description :
The Recombinant Human Granzyme H Protein, CF from R&D Systems is derived from NS0. The Recombinant Human Granzyme H Protein, CF has been validated for the following applications: Enzyme Activity.
target :
Granzyme H
category :
Proteins and Enzymes
buffer :
Supplied as a 0.2 ╡m filtered solution in HEPES, NaCl and Brij-35.
conjugate :
Unconjugated
purity :
>95%, by SDS-PAGE under reducing conditions and visualized by silver stain
species :
Human
observed molecular weight :
Multiple bands between 38-40 kDa, reducing conditions
theoretical molecular weight :
27 kDa
gene symbol :
GZMH
details of functionality :
Measured by its ability to cleave a peptide substrate, Succinyl-Phe-Leu-Phe-ThioBenzyl ester (Suc-FLF-SBzl), in the presence of 5,5Æ-Dithio-bis (2-nitrobenzoic acid) (DTNB). Edwards, K.M. et al . (1999) J. Biol. Chem. 274 :30468. The specific activity is 5,000 pmol/min/╡g, as measured under the described conditions.
endotoxin note :
<1.0 EU per 1 ╡g of the protein by the LAL method.
accessionNumbers :
P20718
applications :
Enzyme Activity
source long :
Mouse myeloma cell line, NS0-derived human Granzyme H protein Glu19-Leu246, with a C-terminal 10-His tag Accession # P20718
source short :
NS0
USD :
456 USD
alt names :
Cathepsin G-like 2, CCP-X, CCP-Xcytotoxic T-lymphocyte-associated serine esterase 1, CGL2, CGL-2, CSP-Ccytotoxin serine protease-C, CTLA1, CTSGL2, CTSGL2granzyme H, Cytotoxic serine protease C, Cytotoxic T-lymphocyte proteinase, EC 3.4.21, EC 3.4.21.-, EC 3.4.21.79, granzyme H (cathepsin G-like 2, protein h-CCPX), GrzH, GZMH
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 6 months from date of receipt, -70 ░C as supplied. 3 months, -70 ░C under sterile conditions after opening.
more info or order :
company information

R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.
browse more products
questions and comments