product summary
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company name :
R&D Systems
product type :
protein
product name :
Recombinant Human IL-26/AK155 Monomer Protein
catalog :
1375-IL-025
quantity :
25 ug
price :
483 USD
more info or order :
R&D Systems product webpage
citations: 6
Reference
Fries A, Saidoune F, Kuonen F, Dupanloup I, Fournier N, Guerra de Souza A, et al. Differentiation of IL-26+ TH17 intermediates into IL-17A producers via epithelial crosstalk in psoriasis. Nat Commun. 2023;14:3878 pubmed publisher
Dang A, Teles R, Weiss D, Parvatiyar K, Sarno E, Ochoa M, et al. IL-26 contributes to host defense against intracellular bacteria. J Clin Invest. 2019;129:1926-1939 pubmed publisher
Corvaisier M, Delneste Y, Jeanvoine H, Preisser L, Blanchard S, Garo E, et al. IL-26 is overexpressed in rheumatoid arthritis and induces proinflammatory cytokine production and Th17 cell generation. PLoS Biol. 2012;10:e1001395 pubmed publisher
Wilson T, Fridlyand J, Yan Y, Penuel E, Burton L, Chan E, et al. Widespread potential for growth-factor-driven resistance to anticancer kinase inhibitors. Nature. 2012;487:505-9 pubmed publisher
Duluc D, Corvaisier M, Blanchard S, Catala L, Descamps P, Gamelin E, et al. Interferon-gamma reverses the immunosuppressive and protumoral properties and prevents the generation of human tumor-associated macrophages. Int J Cancer. 2009;125:367-73 pubmed publisher
Dambacher J, Beigel F, Zitzmann K, De Toni E, Goke B, Diepolder H, et al. The role of the novel Th17 cytokine IL-26 in intestinal inflammation. Gut. 2009;58:1207-17 pubmed publisher
product information
brand :
R&D Systems, a Bio-Techne Brand
catalog number base :
1375-IL
SKU :
1375-IL-025
product name :
Recombinant Human IL-26/AK155 Monomer Protein
Description :
The Recombinant Human IL-26/AK155 Monomer Protein from R&D Systems is derived from E. coli. The Recombinant Human IL-26/AK155 Monomer Protein has been validated for the following applications: Bioactivity.
target :
IL-26/AK155
category :
Proteins and Enzymes
unit size :
25 ug
buffer :
Supplied as a 0.2 µm filtered solution in NaH2PO4, NaCl and Glycerol with BSA as a carrier protein.
conjugate :
Unconjugated
purity :
>95%, by SDS-PAGE under reducing conditions and visualized by silver stain.
species :
Human
theoretical molecular weight :
17.7 kDa
gene symbol :
IL26
details of functionality :
Measured by its ability to induce IL-10 secretion in COLO 205 human colorectal adenocarcinoma cells. Hor, S. et al . (2004) J. Biol. Chem. 279 :33343. The ED50 for this effect is 30-180 ng/mL.
endotoxin note :
<0.10 EU per 1 µg of the protein by the LAL method.
accessionNumbers :
Q9NPH9
applications :
Bioactivity
source :
E. coli-derived Recombinant Human IL-26/AK155 Monomer Protein
USD :
483 USD
alt names :
AK155, AK155IL-26interleukin-26, IL26, interleukin 26, Protein AK155
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 6 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after opening.
more info or order :
R&D Systems product webpage
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.