Recombinant Human IL-26/AK155 Monomer Protein, CF | R&D Systems 1375-IL-025/CF product information

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Human IL-26/AK155 Monomer Protein, CF

catalog :

1375-IL-025/CF

quantity :

25 ug

price :

483 USD

more info or order :

R&D Systems product webpage

citations: 5

Reference
Dang A, Teles R, Weiss D, Parvatiyar K, Sarno E, Ochoa M, et al. IL-26 contributes to host defense against intracellular bacteria. J Clin Invest. 2019;129:1926-1939 pubmed publisher
Corvaisier M, Delneste Y, Jeanvoine H, Preisser L, Blanchard S, Garo E, et al. IL-26 is overexpressed in rheumatoid arthritis and induces proinflammatory cytokine production and Th17 cell generation. PLoS Biol. 2012;10:e1001395 pubmed publisher
Wilson T, Fridlyand J, Yan Y, Penuel E, Burton L, Chan E, et al. Widespread potential for growth-factor-driven resistance to anticancer kinase inhibitors. Nature. 2012;487:505-9 pubmed publisher
Duluc D, Corvaisier M, Blanchard S, Catala L, Descamps P, Gamelin E, et al. Interferon-gamma reverses the immunosuppressive and protumoral properties and prevents the generation of human tumor-associated macrophages. Int J Cancer. 2009;125:367-73 pubmed publisher
Dambacher J, Beigel F, Zitzmann K, De Toni E, Goke B, Diepolder H, et al. The role of the novel Th17 cytokine IL-26 in intestinal inflammation. Gut. 2009;58:1207-17 pubmed publisher

product information

brand :

R&D Systems, a Bio-Techne Brand

catalog number base :

1375-IL/CF

SKU :

1375-IL-025/CF

product name :

Recombinant Human IL-26/AK155 Monomer Protein, CF

Description :

The Recombinant Human IL-26/AK155 Monomer Protein, CF from R&D Systems is derived from E. coli. The Recombinant Human IL-26/AK155 Monomer Protein, CF has been validated for the following applications: Bioactivity.

target :

IL-26/AK155

category :

Proteins and Enzymes

unit size :

25 ug

buffer :

Supplied as a 0.2 µm filtered solution in NaH2PO4, NaCl and Glycerol.

conjugate :

Unconjugated

purity :

>95%, by SDS-PAGE under reducing conditions and visualized by silver stain.

species :

Human

theoretical molecular weight :

17.7 kDa

gene symbol :

IL26

details of functionality :

Measured by its ability to induce IL-10 secretion in COLO 205 human colorectal adenocarcinoma cells. Hor, S. et al . (2004) J. Biol. Chem. 279 :33343. The ED50 for this effect is 30-180 ng/mL.

endotoxin note :

<0.10 EU per 1 µg of the protein by the LAL method.

accessionNumbers :

Q9NPH9

applications :

Bioactivity

source :

E. coli-derived Recombinant Human IL-26/AK155 Monomer Protein

USD :

483 USD

alt names :

AK155, AK155IL-26interleukin-26, IL26, interleukin 26, Protein AK155

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 6 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after opening.

more info or order :

R&D Systems product webpage