product summary
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company name :
R&D Systems
product type :
protein
product name :
Recombinant Human PTP1B Protein, CF
catalog :
1366-PT-050
quantity :
50 ug
price :
394 USD
more info or order :
citations: 2
Reference
Qiang G, Xue S, Yang J, Du G, Pang X, Li X, et al. Identification of a small molecular insulin receptor agonist with potent antidiabetes activity. Diabetes. 2014;63:1394-409 pubmed publisher
Borza C, Chen X, Mathew S, Mont S, Sanders C, Zent R, et al. Integrin {alpha}1{beta}1 promotes caveolin-1 dephosphorylation by activating T cell protein-tyrosine phosphatase. J Biol Chem. 2010;285:40114-24 pubmed publisher
product information
brand :
R&D Systems
master code :
1366-PT
SKU :
1366-PT-050
product name :
Recombinant Human PTP1B Protein, CF
description :
The Recombinant Human PTP1B Protein, CF from R&D Systems is derived from E. coli. The Recombinant Human PTP1B Protein, CF has been validated for the following applications: Enzyme Activity.
target :
PTP1B
category :
Proteins and Enzymes
sizes available :
50 ug
buffer :
Lyophilized from a 0.2 µm filtered solution in HEPES, NaCl and DTT.
conjugate :
Unconjugated
purity :
>95%, by SDS-PAGE under reducing conditions and visualized by silver stain
species :
Human
observed molecular weight :
38 kDa, reducing conditions
theoretical molecular weight :
38 kDa
gene symbol :
PTPN1
details of functionality :
Measured by its ability to dephosphorylate a tyrosine residue in a peptide containing the EGFR Y992 phosphorylation site (Catalog # ES006 ). The specific activity is 15 µmol/min/mg, as measured under the described conditions.
endotoxin note :
<1.0 EU per 1 µg of the protein by the LAL method.
accessionNumbers :
P18031
applications :
Enzyme Activity
source :
E. coli-derived Recombinant Human PTP1B Protein, CF
USD :
388
USD 2023 :
394 USD
alt names :
EC 3.1.3.48, protein tyrosine phosphatase 1B, protein tyrosine phosphatase, non-receptor type 1, Protein-tyrosine phosphatase 1B, PTP-1B, PTP1Bprotein tyrosine phosphatase, placental, PTPN1, tyrosine-protein phosphatase non-receptor type 1
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 6 months from date of receipt, -20 to -70 °C as supplied. 3 months, -20 to -70 °C under sterile conditions after reconstitution.
more info or order :
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.