Recombinant Human PTP1B Protein, CF | R&D Systems 1366-PT-050 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Human PTP1B Protein, CF

catalog :

1366-PT-050

quantity :

50 ug

price :

432 USD

citations: 2

Reference
Qiang G, Xue S, Yang J, Du G, Pang X, Li X, et al. Identification of a small molecular insulin receptor agonist with potent antidiabetes activity. Diabetes. 2014;63:1394-409 pubmed publisher
Borza C, Chen X, Mathew S, Mont S, Sanders C, Zent R, et al. Integrin {alpha}1{beta}1 promotes caveolin-1 dephosphorylation by activating T cell protein-tyrosine phosphatase. J Biol Chem. 2010;285:40114-24 pubmed publisher

product information

master code :

1366-PT

SKU :

1366-PT-050

product name :

Recombinant Human PTP1B Protein, CF

unit size :

50 ug

description :

The Recombinant Human PTP1B Protein, CF from R&D Systems is derived from E. coli. The Recombinant Human PTP1B Protein, CF has been validated for the following applications: Enzyme Activity.

target :

PTP1B

category :

Proteins and Enzymes

buffer :

Lyophilized from a 0.2 ╡m filtered solution in HEPES, NaCl and DTT.

conjugate :

Unconjugated

purity :

>95%, by SDS-PAGE under reducing conditions and visualized by silver stain

species :

Human

observed molecular weight :

38 kDa, reducing conditions

theoretical molecular weight :

38 kDa

gene symbol :

PTPN1

details of functionality :

Measured by its ability to dephosphorylate a tyrosine residue in a peptide containing the EGFR Y992 phosphorylation site (Catalog # ES006 ). The specific activity is 15 ╡mol/min/mg, as measured under the described conditions.

endotoxin note :

<1.0 EU per 1 ╡g of the protein by the LAL method.

accessionNumbers :

P18031

applications :

Enzyme Activity

source long :

E. coli -derived human PTP1B protein Glu2-Asn321, with an N-terminal Met and 6-His tag

source short :

E. coli

USD :

432 USD

alt names :

EC 3.1.3.48, protein tyrosine phosphatase 1B, protein tyrosine phosphatase, non-receptor type 1, Protein-tyrosine phosphatase 1B, PTP-1B, PTP1Bprotein tyrosine phosphatase, placental, PTPN1, tyrosine-protein phosphatase non-receptor type 1

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 6 months from date of receipt, -20 to -70 ░C as supplied. 3 months, -20 to -70 ░C under sterile conditions after reconstitution.