product summary
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company name :
R&D Systems
product type :
protein
product name :
Recombinant Mouse BAFFR/TNFRSF13C Fc Chimera Protein, CF
catalog :
1357-BR-050
quantity :
50 ug
price :
434 USD
more info or order :
R&D Systems product webpage
citations: 4
Reference
Hägglöf T, Sedimbi S, Yates J, Parsa R, Salas B, Harris R, et al. Neutrophils license iNKT cells to regulate self-reactive mouse B cell responses. Nat Immunol. 2016;17:1407-1414 pubmed publisher
Gätjen M, Brand F, Grau M, Gerlach K, Kettritz R, Westermann J, et al. Splenic Marginal Zone Granulocytes Acquire an Accentuated Neutrophil B-Cell Helper Phenotype in Chronic Lymphocytic Leukemia. Cancer Res. 2016;76:5253-65 pubmed publisher
Hong C, Qiu X, Li Y, Huang Q, Zhong Z, Zhang Y, et al. Functional analysis of recombinant calreticulin fragment 39-272: implications for immunobiological activities of calreticulin in health and disease. J Immunol. 2010;185:4561-9 pubmed publisher
Matsushita T, Fujimoto M, Hasegawa M, Matsushita Y, Komura K, Ogawa F, et al. BAFF antagonist attenuates the development of skin fibrosis in tight-skin mice. J Invest Dermatol. 2007;127:2772-80 pubmed
product information
brand :
R&D Systems, a Bio-Techne Brand
catalog number base :
1357-BR
SKU :
1357-BR-050
product name :
Recombinant Mouse BAFFR/TNFRSF13C Fc Chimera Protein, CF
Description :
The Recombinant Mouse BAFFR/TNFRSF13C Fc Chimera Protein, CF from R&D Systems is derived from NS0. The Recombinant Mouse BAFFR/TNFRSF13C Fc Chimera Protein, CF has been validated for the following applications: Bioactivity.
target :
BAFFR/TNFRSF13C
category :
Proteins and Enzymes
unit size :
50 ug
buffer :
Lyophilized from a 0.2 µm filtered solution in PBS.
conjugate :
Unconjugated
purity :
>95%, by SDS-PAGE under reducing conditions and visualized by silver stain.
species :
Mouse
observed molecular weight :
50-55 kDa, reducing conditions
theoretical molecular weight :
33 kDa (monomer)
gene symbol :
TNFRSF13C
details of functionality :
Measured by its ability to inhibit BAFF-mediated proliferation of anti-IgM stimulated mouse B cells. Gross, J.A. et al . (2000) Nature 404 :995. The ED50 for this effect is 2-6 ng/mL in the presence of 1 ng/mL of Recombinant Mouse BAFF R/TNFRSF13C Fc Chimera (Catalog # 8876-BF ).
endotoxin note :
<0.10 EU per 1 µg of the protein by the LAL method.
accessionNumbers :
Q9D8D0
applications :
Bioactivity
source :
NS0-derived Recombinant Mouse BAFFR/TNFRSF13C Fc Chimera Protein
USD :
434 USD
alt names :
BAFF R, BAFFR;BAFF-R;BROMIX;CD268;CVID4;prolixin;Tumor necrosis factor receptor superfamily member 13C, BR3, CD268, TNFRSF13C
storage :
12 months from date of receipt, <= -20 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, <= -20 °C under sterile conditions after reconstitution.
more info or order :
R&D Systems product webpage
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.