Recombinant Mouse CD117/c-kit Fc Chimera Protein, CF | R&D Systems 1356-SR-050 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Mouse CD117/c-kit Fc Chimera Protein, CF

catalog :

1356-SR-050

quantity :

50 ug

price :

468 USD

citations: 1

Reference
SCHMITT M, Schewe M, Sacchetti A, Feijtel D, van de Geer W, Teeuwssen M, et al. Paneth Cells Respond to Inflammation and Contribute to Tissue Regeneration by Acquiring Stem-like Features through SCF/c-Kit Signaling. Cell Rep. 2018;24:2312-2328.e7 pubmed publisher

product information

master code :

1356-SR

SKU :

1356-SR-050

product name :

Recombinant Mouse CD117/c-kit Fc Chimera Protein, CF

unit size :

50 ug

description :

The Recombinant Mouse CD117/c-kit Fc Chimera Protein, CF from R&D Systems is derived from NS0. The Recombinant Mouse CD117/c-kit Fc Chimera Protein, CF has been validated for the following applications: Bioactivity.

target :

CD117/c-kit

category :

Proteins and Enzymes

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS.

conjugate :

Unconjugated

purity :

>95%, by SDS-PAGE under reducing conditions and visualized by silver stain.

species :

Mouse

observed molecular weight :

100-125 kDa, reducing conditions

theoretical molecular weight :

82.6 kDa (monomer)

gene symbol :

Kit

details of functionality :

Measured by its binding ability in a functional ELISA. When Recombinant Mouse CD117/c-kit Fc Chimera is present at 0.5 ╡g/mL, the concentration of Recombinant Mouse SCF/c-kit Ligand (Catalog # 455-MC ) that produces 50% of the optimal binding response is approximately 3-12 ng/mL.

endotoxin note :

<0.10 EU per 1 ╡g of the protein by the LAL method.

accessionNumbers :

P05532

applications :

Bioactivity

source long :

Mouse myeloma cell line, NS0-derived mouse CD117/c-kit protein Mouse CD117/c-kit (Gln26-Thr523) Accession # P05532 IEGRMDP Mouse IgG2A (Glu98-Lys330) N-terminus C-terminus

source short :

NS0

USD :

468 USD

alt names :

CD117, CD117 antigen, ckit, C-Kit, EC 2.7.10, EC 2.7.10.1, KIT, PBT, piebald trait, Proto-oncogene c-Kit, proto-oncogene tyrosine-protein kinase Kit, SCF R, SCFR, SCFRmast/stem cell growth factor receptor, soluble KIT variant 1, Tyrosine-protein kinase Kit, v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog, v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene-like protein

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 3 months, -20 to -70 ░C under sterile conditions after reconstitution.