Recombinant Human IL-17F Protein, CF | R&D Systems 1335-IL-025/CF product information

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Human IL-17F Protein, CF

catalog :

1335-IL-025/CF

quantity :

25 ug

price :

400 USD

more info or order :

R&D Systems product webpage

citations: 8

Reference
Crawford M, Borcherding N, Karandikar N. IL-17 cytokines preferentially act on naïve CD4+ T cells with the IL-17AF heterodimer inducing the greatest functional changes. PLoS ONE. 2023;18:e0285166 pubmed publisher
Nakajima M, Kawaguchi M, Ota K, Fujita J, Matsukura S, Huang S, et al. IL-17F induces IL-6 via TAK1-NFκB pathway in airway smooth muscle cells. Immun Inflamm Dis. 2017;5:124-131 pubmed publisher
Bastidas Coral A, Bakker A, Zandieh Doulabi B, Kleverlaan C, Bravenboer N, Forouzanfar T, et al. Cytokines TNF-α, IL-6, IL-17F, and IL-4 Differentially Affect Osteogenic Differentiation of Human Adipose Stem Cells. Stem Cells Int. 2016;2016:1318256 pubmed publisher
Ling Y, Cypowyj S, Aytekin C, Galicchio M, Camcioglu Y, Nepesov S, et al. Inherited IL-17RC deficiency in patients with chronic mucocutaneous candidiasis. J Exp Med. 2015;212:619-31 pubmed publisher
Kisand K, Bøe Wolff A, Podkrajsek K, Tserel L, Link M, Kisand K, et al. Chronic mucocutaneous candidiasis in APECED or thymoma patients correlates with autoimmunity to Th17-associated cytokines. J Exp Med. 2010;207:299-308 pubmed publisher
Xu G, Zhang L, Wang D, Xu R, Liu Z, Han D, et al. Opposing roles of IL-17A and IL-25 in the regulation of TSLP production in human nasal epithelial cells. Allergy. 2010;65:581-9 pubmed publisher
Zrioual S, Ecochard R, Tournadre A, Lenief V, Cazalis M, Miossec P. Genome-wide comparison between IL-17A- and IL-17F-induced effects in human rheumatoid arthritis synoviocytes. J Immunol. 2009;182:3112-20 pubmed publisher
Watanabe H, Kawaguchi M, Fujishima S, Ogura M, Matsukura S, Takeuchi H, et al. Functional characterization of IL-17F as a selective neutrophil attractant in psoriasis. J Invest Dermatol. 2009;129:650-6 pubmed publisher

product information

master code :

1335-IL/CF

SKU :

1335-IL-025/CF

product name :

Recombinant Human IL-17F Protein, CF

unit size :

25 ug

description :

The Recombinant Human IL-17F Protein, CF from R&D Systems is derived from E. coli. The Recombinant Human IL-17F Protein, CF has been validated for the following applications: Bioactivity.

target :

IL-17F

category :

Proteins and Enzymes

buffer :

Lyophilized from a 0.2 ╡m filtered solution in Acetonitrile and TFA.

conjugate :

Unconjugated

purity :

>97%, by SDS-PAGE under reducing conditions and visualized by silver stain.

species :

Human

theoretical molecular weight :

15 kDa (monomer)

gene symbol :

IL17F

details of functionality :

Measured by its ability to induce IL-6 secretion by NIH-3T3 mouse embryonic fibroblast cells. The ED50 for this effect is 8-40 ng/mL.

endotoxin note :

<0.10 EU per 1 ╡g of the protein by the LAL method.

accessionNumbers :

Q96PD4

applications :

Bioactivity

source long :

E. coli -derived human IL-17F protein Arg31-Gln163, with an N-terminal Met

source short :

E. coli

extended description :

An economically priced, Mammalian-expressed Version Available!

USD :

400 USD

product details :

An economically priced, Mammalian-expressed Version Available!

alt names :

Cytokine ML-1, IL17F, IL-17Finterleukin-17F, interleukin 17F

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 3 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage