Recombinant Human IGFBP-rp1/IGFBP-7 (K95R) Protein, CF | R&D Systems 1334-B7-025 product information

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Human IGFBP-rp1/IGFBP-7 (K95R) Protein, CF

catalog :

1334-B7-025

quantity :

25 ug

price :

405 USD

more info or order :

R&D Systems product webpage

citations: 5

Reference
Infante A, RodrÃguez C. Secretome analysis of in vitro aged human mesenchymal stem cells reveals IGFBP7 as a putative factor for promoting osteogenesis. Sci Rep. 2018;8:4632 pubmed publisher
Laranjeira A, de Vasconcellos J, Sodek L, Spago M, Fornazim M, Tone L, et al. IGFBP7 participates in the reciprocal interaction between acute lymphoblastic leukemia and BM stromal cells and in leukemia resistance to asparaginase. Leukemia. 2012;26:1001-11 pubmed publisher
Gunawardana C, Kuk C, Smith C, Batruch I, Soosaipillai A, Diamandis E. Comprehensive analysis of conditioned media from ovarian cancer cell lines identifies novel candidate markers of epithelial ovarian cancer. J Proteome Res. 2009;8:4705-13 pubmed publisher
Jiang W, Xiang C, Cazacu S, Brodie C, Mikkelsen T. Insulin-like growth factor binding protein 7 mediates glioma cell growth and migration. Neoplasia. 2008;10:1335-42 pubmed
Cortesio C, Jiang W. Mannan-binding lectin-associated serine protease 3 cleaves synthetic peptides and insulin-like growth factor-binding protein 5. Arch Biochem Biophys. 2006;449:164-70 pubmed

image

image 1 :

Recombinant Human IGFBP-rp1/IGFBP-7 (K95R) Protein Binding Activity

product information

brand :

R&D Systems

master code :

1334-B7

SKU :

1334-B7-025

product name :

Recombinant Human IGFBP-rp1/IGFBP-7 (K95R) Protein, CF

description :

The Recombinant Human IGFBP-rp1/IGFBP-7 (K95R) Protein, CF from R&D Systems is derived from NS0. The Recombinant Human IGFBP-rp1/IGFBP-7 (K95R) Protein, CF has been validated for the following applications: Binding Activity.

target :

IGFBP-rp1/IGFBP-7

category :

Proteins and Enzymes

sizes available :

25 ug

buffer :

Lyophilized from a 0.2 µm filtered solution in PBS.

conjugate :

Unconjugated

purity :

>90%, by SDS-PAGE under reducing conditions and visualized by silver stain.

species :

Human

observed molecular weight :

36 kDa, reducing conditions

theoretical molecular weight :

27.5 kDa

gene symbol :

IGFBP7

details of functionality :

Measured by its ability to bind 6Ckine/CCL21 in a functional ELISA. Nagakubo, D. et al . (2003) J. Immunol. 171 :553. When Recombinant Human (rh) IGFBP-rp1/IGFBP-7 (K95R) is immobilized at 500 ng/mL (100 µL/well), the concentration of Recombinant Human CCL21/6Ckine (Catalog # 366-6C ) that produces 50% optimal binding response is found to be approximately 4-20 ng/mL.

endotoxin note :

<0.01 EU per 1 µg of the protein by the LAL method.

accessionNumbers :

Q16270

applications :

Binding Activity

source :

NS0-derived Recombinant Human IGFBP-rp1/IGFBP-7 (K95R) Protein, CF

USD :

405 USD

alt names :

angiomodulin, FSTL2, IBP-7, IGFBP7, IGFBP-7, IGFBP-7PGI2-stimulating factor, IGFBP-7v, IGFBPrp1, IGFBP-rP1, insulin-like growth factor binding protein 7, insulin-like growth factor-binding protein 7, Mac25, MAC25 protein, MAC25IGF-binding protein 7, Prostacyclin-stimulating factor, PSF, PSFAGM, TAF, Tumor-derived adhesion factor

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage