product summary
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company name :
R&D Systems
product type :
protein
product name :
Bovine FGF basic/FGF2/bFGF Protein
catalog :
133-FB-025
quantity :
25 ug
price :
466 USD
more info or order :
R&D Systems product webpage
citations: 10
Reference
Tsissios G, Sallese A, Perez Estrada J, Tangeman J, Chen W, Smucker B, et al. Macrophages modulate fibrosis during newt lens regeneration. bioRxiv. 2023;: pubmed publisher
Tangeman J, P xe9 rez Estrada J, Van Zeeland E, Liu L, Danciutiu A, Grajales Esquivel E, et al. A Stage-Specific OTX2 Regulatory Network and Maturation-Associated Gene Programs Are Inherent Barriers to RPE Neural Competency. Front Cell Dev Biol. 2022;10:875155 pubmed publisher
Scott R, Arostegui M, Schweitzer R, Rossi F, Underhill T. Hic1 Defines Quiescent Mesenchymal Progenitor Subpopulations with Distinct Functions and Fates in Skeletal Muscle Regeneration. Cell Stem Cell. 2019;25:797-813.e9 pubmed publisher
Gong X, Liu W, Wu L, Ma Z, Wang Y, Yu S, et al. Transcriptional repressor GATA binding 1-mediated repression of SRY-box 2 expression suppresses cancer stem cell functions and tumor initiation. J Biol Chem. 2018;293:18646-18654 pubmed publisher
Boswell B, Korol A, West Mays J, Musil L. Dual function of TGF? in lens epithelial cell fate: implications for secondary cataract. Mol Biol Cell. 2017;28:907-921 pubmed publisher
Tsai S, Bouwman B, Ang Y, Kim S, Lee D, Lemischka I, et al. Single transcription factor reprogramming of hair follicle dermal papilla cells to induced pluripotent stem cells. Stem Cells. 2011;29:964-71 pubmed publisher
Boswell B, Overbeek P, Musil L. Essential role of BMPs in FGF-induced secondary lens fiber differentiation. Dev Biol. 2008;324:202-12 pubmed publisher
Zheng J, Wen Y, Song Y, Wang K, Chen D, Magness R. Activation of multiple signaling pathways is critical for fibroblast growth factor 2- and vascular endothelial growth factor-stimulated ovine fetoplacental endothelial cell proliferation. Biol Reprod. 2008;78:143-50 pubmed
Horst A, Ito W, Dabelstein J, Schumacher U, Sander H, Turbide C, et al. Carcinoembryonic antigen-related cell adhesion molecule 1 modulates vascular remodeling in vitro and in vivo. J Clin Invest. 2006;116:1596-605 pubmed
Collombet J, Four E, Burckhart M, Masqueliez C, Bernabé D, Baubichon D, et al. Effect of cytokine treatment on the neurogenesis process in the brain of soman-poisoned mice. Toxicology. 2005;210:9-23 pubmed
product information
brand :
R&D Systems, a Bio-Techne brand
catalog number base :
133-FB
SKU :
133-FB-025
product name :
Bovine FGF basic/FGF2/bFGF Protein
description :
The Bovine FGF basic/FGF2/bFGF Protein from R&D Systems is derived from Bovine Brain. The Bovine FGF basic/FGF2/bFGF Protein has been validated for the following applications: Bioactivity.
target :
FGF basic/FGF2/bFGF
unit size :
25 ug
category :
Proteins and Enzymes
buffer :
Lyophilized from a 0.2 µm filtered solution in Tris-HCl and NaCl with BSA as a carrier protein.
conjugate :
Unconjugated
purity :
>97%, by SDS-PAGE under reducing conditions and visualized by silver stain.
species :
Bovine
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution.
observed molecular weight :
18 kDa, reducing conditions
gene symbol :
FGF2
details of functionality :
Measured in a cell proliferation assay using NR6R-3T3 mouse fibroblast cells. Rizzino, A. et al . (1988) Cancer Res. 48 :4266; Thomas, K. et al . (1987) Methods Enzymol. 147 :120. The ED50 for this effect is 0.125-0.625 ng/mL.
endotoxin note :
<1.0 EU per 1 µg of the protein by the LAL method.
applications :
Bioactivity
product keywords :
133-FB, bFGF basic,, 133FB, cytokinegrowthfact, FGFbasic, FGFb, bFGF, FGF-AS, ASFGF2, cytokine, cytokines, FGF b, ss-FGF, -FGF, FGF, bFGF2, Fibroblast Growth Factor 2, Heparin-Binding Growth Factor 2, HBGF-2, bFGF, Prostatropin, Basic Fibroblast Growth Factor, NUDT6, GFG1
source :
Bovine Brain
USD :
453
USD 2025 :
466 USD
alt names :
Basic fibroblast growth factor, basic fibroblast growth factor bFGF, bFGF, FGF2, FGF-2, FGFBprostatropin, fibroblast growth factor 2 (basic), HBGF-2, heparin-binding growth factor 2, Prostatropin
more info or order :
R&D Systems product webpage
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.