product summary
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company name :
R&D Systems
product type :
protein
product name :
Recombinant Human BIM (Long Form) Protein, CF
catalog :
1325-BL-050
quantity :
50 ug
price :
432 USD
more info or order :
R&D Systems product webpage
citations: 1
Reference
Iwata A, De Claro R, Morgan Stevenson V, Tupper J, Schwartz B, Liu L, et al. Extracellular administration of BCL2 protein reduces apoptosis and improves survival in a murine model of sepsis. PLoS ONE. 2011;6:e14729 pubmed publisher
product information
master code :
1325-BL
SKU :
1325-BL-050
product name :
Recombinant Human BIM (Long Form) Protein, CF
unit size :
50 ug
description :
The Recombinant Human BIM (Long Form) Protein, CF from R&D Systems is derived from E. coli. The Recombinant Human BIM (Long Form) Protein, CF has been validated for the following applications: Bioactivity.
target :
BIM Long (BIM L)
category :
Proteins and Enzymes
buffer :
Supplied as a 0.2 ╡m filtered solution in HEPES-KOH, DTT, KCl and Glycerol.
conjugate :
Unconjugated
purity :
>95%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie« Blue Staining.
species :
Human
observed molecular weight :
13-16 kDa and 30-35 kDa, reducing conditions
theoretical molecular weight :
14.3 kDa
gene symbol :
BCL2L11
details of functionality :
Measured by its ability to neutralize anti-apoptotic Bcl-2 family member inhibition of Recombinant Human BID Caspase-8-cleaved (Catalog # 882-B8 )-mediated Cytochrome c release from isolated mitochondria. Release of Cytochrome c is quantified using the Rat/Mouse Cytochrome c Quantikine ELISA (Catalog # MCTC0 ). The typical EC50 value in this assay is 0.1-2 ╡M. Optimal dose should be determined for each application.
accessionNumbers :
NP_006529
applications :
Bioactivity
source long :
E. coli -derived human BIM Long (BIM L) protein Ala2-Arg120, with an N-terminal 6-His tag
source short :
E. coli
USD :
432 USD
alt names :
BAM, BCL2L11, BIM, BOD
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 6 months from date of receipt, -20 to -70 ░C as supplied. 3 months, -20 to -70 ░C under sterile conditions after opening.
more info or order :
R&D Systems product webpage
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.