product summary
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company name :
R&D Systems
product type :
protein
product name :
Recombinant Mouse Thrombopoietin R Fc Chimera Protein, CF
catalog :
1317-TR-050
quantity :
50 ug
price :
447 USD
more info or order :
R&D Systems product webpage
citations: 1
Reference
Nakamura Ishizu A, Takubo K, Fujioka M, Suda T. Megakaryocytes are essential for HSC quiescence through the production of thrombopoietin. Biochem Biophys Res Commun. 2014;454:353-7 pubmed
product information
brand :
R&D Systems, a Bio-Techne Brand
catalog number base :
1317-TR
SKU :
1317-TR-050
product name :
Recombinant Mouse Thrombopoietin R Fc Chimera Protein, CF
Description :
The Recombinant Mouse Thrombopoietin R Fc Chimera Protein, CF from R&D Systems is derived from NS0. The Recombinant Mouse Thrombopoietin R Fc Chimera Protein, CF has been validated for the following applications: Bioactivity.
target :
Thrombopoietin R/Tpo R
category :
Proteins and Enzymes
unit size :
50 ug
buffer :
Lyophilized from a 0.2 µm filtered solution in PBS and EDTA.
conjugate :
Unconjugated
purity :
>90%, by SDS-PAGE under reducing conditions and visualized by silver stain
species :
Mouse
observed molecular weight :
95-110 kDa, reducing conditions
theoretical molecular weight :
79.6 kDa (monomer)
gene symbol :
Mpl
details of functionality :
Measured by its ability to inhibit the Tpo-dependent proliferation of MO7e human megakaryocytic leukemic cells. The ED50 for this effect is 0.1-0.4 µg/mL in the presence of 4 ng/mL of Recombinant Mouse Thrombopoietin/Tpo (Catalog # 488-TO ).
endotoxin note :
<0.10 EU per 1 µg of the protein by the LAL method.
accessionNumbers :
CAA52031
applications :
Bioactivity
source :
NS0-derived Recombinant Mouse Thrombopoietin R Fc Chimera Protein
USD :
447 USD
alt names :
CD110, CD110 antigen, C-MPL, MPL, MPLV, Myeloproliferative leukemia protein, myeloproliferative leukemia virus oncogene, Proto-oncogene c-Mpl, thrombopoietin receptor, TpoR, TPO-R, TPORMPLV
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 3 months, 2 to 8 °C under sterile conditions after reconstitution.
more info or order :
R&D Systems product webpage
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.