Recombinant Rat IL-22 Protein | R&D Systems 1316-RL-010 product information

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Rat IL-22 Protein

catalog :

1316-RL-010

quantity :

10 ug

price :

432 USD

more info or order :

R&D Systems product webpage

citations: 3

Reference
Gaudino S, Singh A, Huang H, Padiadpu J, Jean Pierre M, Kempen C, et al. Intestinal IL-22RA1 signaling regulates intrinsic and systemic lipid and glucose metabolism to alleviate obesity-associated disorders. Nat Commun. 2024;15:1597 pubmed publisher
Lindahl H, Guerreiro Cacais A, Bedri S, Linnerbauer M, Lindén M, Abdelmagid N, et al. IL-22 Binding Protein Promotes the Disease Process in Multiple Sclerosis. J Immunol. 2019;203:888-898 pubmed publisher
Hu B, Shi C, Lei R, Lu D, Luo W, Qin S, et al. Interleukin-22 ameliorates liver fibrosis through miR-200a/beta-catenin. Sci Rep. 2016;6:36436 pubmed publisher

product information

master code :

1316-RL

SKU :

1316-RL-010

product name :

Recombinant Rat IL-22 Protein

unit size :

10 ug

description :

The Recombinant Rat IL-22 Protein from R&D Systems is derived from E. coli. The Recombinant Rat IL-22 Protein has been validated for the following applications: Bioactivity.

target :

IL-22

category :

Proteins and Enzymes

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS with BSA as a carrier protein.

conjugate :

Unconjugated

purity :

>97%, by SDS-PAGE under reducing conditions and visualized by silver stain

species :

Rat

theoretical molecular weight :

16.7 kDa

gene symbol :

Il22

details of functionality :

Measured by its ability to induce IL-10 secretion in COLO 205 human colorectal adenocarcinoma cells. Nagalakshmi, M.L. et al . (2004) International Immunopharmacology 4 :679. The ED50 for this effect is 150-750ápg/mL.

endotoxin note :

<0.1 EU per 1 ╡g of the protein by the LAL method.

accessionNumbers :

Q198B4

applications :

Bioactivity

source long :

E. coli -derived rat IL-22 protein Leu27-Val172, with an N-terminal Met

source short :

E. coli

USD :

432 USD

alt names :

Cytokine Zcyto18, IL-10-related T-cell-derived inducible factor, IL22, IL-D110, IL-TIF, ILTIFIL-10-related T-cell-derived-inducible factor, IL-TIFMGC79382, interleukin 22, interleukin-22, MGC79384, TIFa, TIFIL-23, zcyto18

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 3 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage