This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
R&D Systems
product type :
protein
product name :
Recombinant Human Serpin A3 Protein, CF
catalog :
1295-PI
quantity :
10 ug
price :
339 USD
citations: 3
Reference
Silva L, Stoll T, Kryza T, Stephens C, Hastie M, Irving Rodgers H, et al. Mass spectrometry-based determination of Kallikrein-related peptidase 7 (KLK7) cleavage preferences and subsite dependency. Sci Rep. 2017;7:6789 pubmed publisher
Memari N, Jiang W, Diamandis E, Luo L. Enzymatic properties of human kallikrein-related peptidase 12 (KLK12). Biol Chem. 2007;388:427-35 pubmed
Cortesio C, Jiang W. Mannan-binding lectin-associated serine protease 3 cleaves synthetic peptides and insulin-like growth factor-binding protein 5. Arch Biochem Biophys. 2006;449:164-70 pubmed
product information
brand :
R&D Systems
master code :
1295-PI
SKU :
1295-PI-010
product name :
Recombinant Human Serpin A3 Protein, CF
description :
The Recombinant Human Serpin A3 Protein, CF from R&D Systems is derived from NS0. The Recombinant Human Serpin A3 Protein, CF has been validated for the following applications: Inhibition Activity.
target :
Serpin A3/alpha 1-Antichymotrypsin
category :
Proteins and Enzymes
unit size :
10 ug
buffer :
Lyophilized from a 0.2 µm filtered solution in HEPES and NaCl.
conjugate :
Unconjugated
purity :
>90%, by SDS-PAGE under reducing conditions and visualized by silver stain
species :
Human
observed molecular weight :
60-65 kDa, reducing conditions
theoretical molecular weight :
46 kDa
gene symbol :
SERPINA3
details of functionality :
Measured by its ability to inhibit chymotrypsin cleavage of a fluorogenic peptide substrate MCA-RPKPVE-Nval-WRK(Dnp)-NH2 (Catalog # ES002 ). The IC50 value is 8 nM, as measured under the described conditions.
endotoxin note :
<1.0 EU per 1 µg of the protein by the LAL method.
catalog number base :
1295-PI
accessionNumbers :
P01011
applications :
Inhibition Activity
source :
Mouse myeloma cell line, NS0-derived human Serpin A3/alpha 1-Antichymotrypsin protein Asn26-Ala423, with a C-terminal 10-His tag
2020 USD :
339
2021 USD :
339 USD
alt names :
AACTMGC88254, ACTGIG25, alpha 1-Antichymotrypsin, alpha-1-antichymotrypsin, antitrypsin), member 3, Cell growth-inhibiting gene 24/25 protein, growth-inhibiting protein 24, growth-inhibiting protein 25, member 3, serine (or cysteine) proteinase inhibitor, clade A (alpha-1 antiproteinase, serine (or cysteine) proteinase inhibitor, clade A, member 3, Serpin A3, serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin)
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 6 months from date of receipt, -20 to -70 °C as supplied. 3 months, -20 to -70 °C under sterile conditions after reconstitution.
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.