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company name :
R&D Systems
product type :
protein
product name :
Recombinant Human IL-23 Protein
catalog :
1290-IL-010
quantity :
10 ug
price :
367 USD
more info or order :
citations: 105
Reference
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Teunissen M, Munneke J, Bernink J, Spuls P, Res P, te Velde A, et al. Composition of innate lymphoid cell subsets in the human skin: enrichment of NCR(+) ILC3 in lesional skin and blood of psoriasis patients. J Invest Dermatol. 2014;134:2351-2360 pubmed publisher
Gresnigt M, Bozza S, Becker K, Joosten L, Abdollahi Roodsaz S, van der Berg W, et al. A polysaccharide virulence factor from Aspergillus fumigatus elicits anti-inflammatory effects through induction of Interleukin-1 receptor antagonist. PLoS Pathog. 2014;10:e1003936 pubmed publisher
Prigent L, Robineau M, Jouneau S, Morzadec C, Louarn L, Vernhet L, et al. The aryl hydrocarbon receptor is functionally upregulated early in the course of human T-cell activation. Eur J Immunol. 2014;44:1330-40 pubmed publisher
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image
image 1 :
R&D Systems 1290-IL-010 image 1
Recombinant Human IL-23 Protein Bioactivity
product information
brand :
R&D Systems
master code :
1290-IL
SKU :
1290-IL-010
product name :
Recombinant Human IL-23 Protein
description :
The Recombinant Human IL-23 Protein from R&D Systems is derived from Sf 21 (baculovirus). The Recombinant Human IL-23 Protein has been validated for the following applications: Bioactivity.
target :
IL-23
category :
Proteins and Enzymes
sizes available :
10 ug
buffer :
Lyophilized from a 0.2 µm filtered solution in MES, NaCl and EDTA with BSA as a carrier protein.
conjugate :
Unconjugated
purity :
>95%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie® Blue Staining.
species :
Human
observed molecular weight :
65 kDa, 43-45 kDa and 20 kDa, reducing conditions
theoretical molecular weight :
55.0 kDa (IL-23 single chain); 36.5 kDa (p40) 18.5 kDa (p19)
gene symbol :
IL23A
details of functionality :
Measured by its ability to induce IL-17 secretion by mouse splenocytes. Aggarwal, S. et al . (2003) J. Biol. Chem. 278 :1910. The ED50 for this effect is 0.05-0.3 ng/mL.
endotoxin note :
<1.0 EU per 1 µg of the protein by the LAL method.
accessionNumbers :
P29460 (p40) AAG37232 (p19)
applications :
Bioactivity
source :
Sf 21 (baculovirus)-derived Recombinant Human IL-23 Protein
USD :
367
USD 2023 :
367 USD
alt names :
IL23, IL-23, IL-23 p19/IL-12 p40, IL-23A, IL-23-A, IL-23p19, IL-23p19/IL-12p40, IL23P19P19, interleukin 23 p19 subunit, interleukin 23, alpha subunit p19, interleukin-23 subunit alpha, Interleukin-23 subunit p19, JKA3 induced upon T-cell activation, MGC79388, SGRF, SGRFIL-23 subunit alpha
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution.
more info or order :
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.