Recombinant Chicken Netrin-1 Protein | R&D Systems 128-N1-025 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Chicken Netrin-1 Protein

catalog :

128-N1-025

quantity :

25 ug

price :

468 USD

citations: 8

Reference
Huang C, Lien C, Cheng C, Yen T, Chen C, Tsaur M. K+ Channel Kv3.4 Is Essential for Axon Growth by Limiting the Influx of Ca2+ into Growth Cones. J Neurosci. 2017;37:4433-4449 pubmed publisher
Yang X, Li S, Zhong J, Zhang W, Hua X, Li B, et al. CD151 mediates netrin-1-induced angiogenesis through the Src-FAK-Paxillin pathway. J Cell Mol Med. 2017;21:72-80 pubmed publisher
Li J, Duarte T, Kocabas A, Works M, McConnell S, Hynes M. Evidence for topographic guidance of dopaminergic axons by differential Netrin-1 expression in the striatum. Mol Cell Neurosci. 2014;61:85-96 pubmed publisher
van Gils J, Ramkhelawon B, Fernandes L, Stewart M, Guo L, Seibert T, et al. Endothelial expression of guidance cues in vessel wall homeostasis dysregulation under proatherosclerotic conditions. Arterioscler Thromb Vasc Biol. 2013;33:911-9 pubmed publisher
Lejmi E, Leconte L, Pedron Mazoyer S, Ropert S, Raoul W, Lavalette S, et al. Netrin-4 inhibits angiogenesis via binding to neogenin and recruitment of Unc5B. Proc Natl Acad Sci U S A. 2008;105:12491-6 pubmed publisher
Hutchins B, Kalil K. Differential outgrowth of axons and their branches is regulated by localized calcium transients. J Neurosci. 2008;28:143-53 pubmed publisher
Ly N, Komatsuzaki K, Fraser I, Tseng A, Prodhan P, Moore K, et al. Netrin-1 inhibits leukocyte migration in vitro and in vivo. Proc Natl Acad Sci U S A. 2005;102:14729-34 pubmed
Tsai H, Tessier Lavigne M, Miller R. Netrin 1 mediates spinal cord oligodendrocyte precursor dispersal. Development. 2003;130:2095-105 pubmed

product information

master code :

128-N1

SKU :

128-N1-025

product name :

Recombinant Chicken Netrin-1 Protein

unit size :

25 ug

description :

The Recombinant Chicken Netrin-1 Protein from R&D Systems is derived from NS0. The Recombinant Chicken Netrin-1 Protein has been validated for the following applications: Binding Activity.

target :

Netrin-1

category :

Proteins and Enzymes

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS with BSA as a carrier protein.

conjugate :

Unconjugated

purity :

>95%, by SDS-PAGE under reducing conditions and visualized by silver stain

species :

Chicken

observed molecular weight :

75-85 kDa, reducing conditions

theoretical molecular weight :

66.3 kDa

gene symbol :

NTN1

details of functionality :

Measured by its binding ability in a functional ELISA. Immobilized rrUNC5H2/Fc Chimera at 5 ╡g/mL (100 ╡L/well) can bind rcNetrin-1 with a linear range of 6-400 ng/mL.

endotoxin note :

<1.0 EU per 1 ╡g of the protein by the LAL method.

accessionNumbers :

Q90922

applications :

Binding Activity

source long :

Mouse myeloma cell line, NS0-derived chicken Netrin-1 protein Chicken Netrin-1 (Gly26 - Ala606) Accession # Q90922 DIEGRGGGSGGGSGGGS 10-His tag N-terminus C-terminus

source short :

NS0

USD :

468 USD

alt names :

netrin 1, netrin-1, Netrin1, NTN1, NTN1Lnetrin 1, mouse, homolog of

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 3 months, -20 to -70 ░C under sterile conditions after reconstitution.