Recombinant Human Dkk-4 Protein, CF | R&D Systems 1269-DK-010/CF product information

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Human Dkk-4 Protein, CF

catalog :

1269-DK-010/CF

quantity :

10 ug

price :

483 USD

more info or order :

R&D Systems product webpage

citations: 3

Reference
Priestley R, Cheung J, Murphy E, Ehebauer M, Davis J, Di Daniel E. A novel high-content imaging-based technique for measuring binding of Dickkopf-1 to low-density lipoprotein receptor-related protein 6. J Pharmacol Toxicol Methods. 2019;95:47-55 pubmed publisher
Wilson T, Fridlyand J, Yan Y, Penuel E, Burton L, Chan E, et al. Widespread potential for growth-factor-driven resistance to anticancer kinase inhibitors. Nature. 2012;487:505-9 pubmed publisher
Zenzmaier C, Marksteiner J, Kiefer A, Berger P, Humpel C. Dkk-3 is elevated in CSF and plasma of Alzheimer's disease patients. J Neurochem. 2009;110:653-61 pubmed publisher

image

image 1 :

Recombinant Human Dkk-4 Protein Bioactivity

product information

brand :

R&D Systems, a Bio-Techne Brand

catalog number base :

1269-DK/CF

SKU :

1269-DK-010/CF

product name :

Recombinant Human Dkk-4 Protein, CF

Description :

The Recombinant Human Dkk-4 Protein, CF from R&D Systems is derived from NS0. The Recombinant Human Dkk-4 Protein, CF has been validated for the following applications: Bioactivity.

target :

Dkk-4

category :

Proteins and Enzymes

unit size :

10 ug

buffer :

Lyophilized from a 0.2 µm filtered solution in Tris-Citrate and NaCl.

conjugate :

Unconjugated

purity :

>95%, by SDS-PAGE under reducing conditions and visualized by silver stain.

species :

Human

observed molecular weight :

35 kDa, reducing conditions

theoretical molecular weight :

24.4 kDa

gene symbol :

DKK4

details of functionality :

Measured by its ability to inhibit Wnt induced TCF reporter activity in HEK293 human embryonic kidney cells. Recombinant Human Dkk-4 (Catalog # 1269-DK/CF) inhibits a constant dose of 500 ng/mL of Recombinant Human Wnt-3a (Catalog # 5036-WN ). The ED50 for this effect is 150-900 ng/mL.

endotoxin note :

<0.10 EU per 1 µg of the protein by the LAL method.

accessionNumbers :

NP_055235

applications :

Bioactivity

source :

NS0-derived Recombinant Human Dkk-4 Protein

USD :

483 USD

alt names :

dickkopf (Xenopus laevis) homolog 4, dickkopf homolog 4 (Xenopus laevis), dickkopf-4, dickkopf-related protein 4, Dkk4, DKK-4, hDkk-4, MGC129562, MGC129563

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 3 months, 2 to 8 °C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage