Recombinant Human Serpin A1/alpha-1-Antitrypsin Protein, CF | R&D Systems 1268-PI product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Human Serpin A1/alpha-1-Antitrypsin Protein, CF

catalog :

1268-PI

quantity :

10 ug

price :

339 USD

citations: 3

Reference
Rooryck C, Diaz Font A, Osborn D, Chabchoub E, Hernandez Hernandez V, Shamseldin H, et al. Mutations in lectin complement pathway genes COLEC11 and MASP1 cause 3MC syndrome. Nat Genet. 2011;43:197-203 pubmed publisher
Memari N, Jiang W, Diamandis E, Luo L. Enzymatic properties of human kallikrein-related peptidase 12 (KLK12). Biol Chem. 2007;388:427-35 pubmed
Cortesio C, Jiang W. Mannan-binding lectin-associated serine protease 3 cleaves synthetic peptides and insulin-like growth factor-binding protein 5. Arch Biochem Biophys. 2006;449:164-70 pubmed

product information

brand :

R&D Systems

master code :

1268-PI

SKU :

1268-PI-010

product name :

Recombinant Human Serpin A1/alpha-1-Antitrypsin Protein, CF

description :

The Recombinant Human Serpin A1/alpha-1-Antitrypsin Protein, CF from R&D Systems is derived from NS0. The Recombinant Human Serpin A1/alpha-1-Antitrypsin Protein, CF has been validated for the following applications: Inhibition Activity.

target :

Serpin A1/alpha 1-Antitrypsin

category :

Proteins and Enzymes

unit size :

10 ug

buffer :

Lyophilized from a 0.2 µm filtered solution in Tris, NaCl and CaCl2 with Trehalose.

conjugate :

Unconjugated

purity :

>95%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie® Blue Staining.

species :

Human

observed molecular weight :

60 kDa, reducing conditions

theoretical molecular weight :

46 kDa

gene symbol :

SERPINA1

details of functionality :

Measured by its ability to inhibit trypsin cleavage of a fluorogenic peptide substrate, Mca-RPKPVE-Nval-WRK(Dnp)-NH2 (Catalog # ES002 ). The IC50 value is approximately 5.0 nM, as measured under the described conditions.

endotoxin note :

<1.0 EU per 1 µg of the protein by the LAL method.

catalog number base :

1268-PI

accessionNumbers :

P01009

applications :

Inhibition Activity

source :

Mouse myeloma cell line, NS0-derived human Serpin A1/alpha 1-Antitrypsin protein Glu25-Lys418, with a C-terminal 10-His tag

2020 USD :

339

2021 USD :

339 USD

alt names :

A1A, A1AT, AATMGC23330, alpha 1-Antitrypsin, alpha 1-Proteinase Inhibitor, Alpha-1 protease inhibitor, Alpha-1-antiproteinase, alpha-1-antitrypsin, antitrypsin), member 1, member 1, PIMGC9222, serine (or cysteine) proteinase inhibitor, clade A (alpha-1 antiproteinase, serine (or cysteine) proteinase inhibitor, clade A, member 1, Serpin A1, serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin)

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 6 months from date of receipt, -20 to -70 °C as supplied. 3 months, -20 to -70 °C under sterile conditions after reconstitution.