Recombinant Human Serpin A1/alpha-1-Antitrypsin Protein, CF | R&D Systems 1268-PI-010 product information

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Human Serpin A1/alpha-1-Antitrypsin Protein, CF

catalog :

1268-PI-010

quantity :

10 ug

price :

394 USD

more info or order :

R&D Systems product webpage

citations: 3

Reference
Rooryck C, Diaz Font A, Osborn D, Chabchoub E, Hernandez Hernandez V, Shamseldin H, et al. Mutations in lectin complement pathway genes COLEC11 and MASP1 cause 3MC syndrome. Nat Genet. 2011;43:197-203 pubmed publisher
Memari N, Jiang W, Diamandis E, Luo L. Enzymatic properties of human kallikrein-related peptidase 12 (KLK12). Biol Chem. 2007;388:427-35 pubmed
Cortesio C, Jiang W. Mannan-binding lectin-associated serine protease 3 cleaves synthetic peptides and insulin-like growth factor-binding protein 5. Arch Biochem Biophys. 2006;449:164-70 pubmed

image

image 1 :

Recombinant Human Serpin A1/alpha-1-Antitrypsin Protein Enzyme Activity

product information

brand :

R&D Systems

master code :

1268-PI

SKU :

1268-PI-010

product name :

Recombinant Human Serpin A1/alpha-1-Antitrypsin Protein, CF

description :

The Recombinant Human Serpin A1/alpha-1-Antitrypsin Protein, CF from R&D Systems is derived from NS0. The Recombinant Human Serpin A1/alpha-1-Antitrypsin Protein, CF has been validated for the following applications: Inhibition Activity.

target :

Serpin A1/alpha 1-Antitrypsin

category :

Proteins and Enzymes

sizes available :

10 ug

buffer :

Lyophilized from a 0.2 µm filtered solution in Tris, NaCl and CaCl2 with Trehalose.

conjugate :

Unconjugated

purity :

>95%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie® Blue Staining.

species :

Human

observed molecular weight :

60 kDa, reducing conditions

theoretical molecular weight :

46 kDa

gene symbol :

SERPINA1

details of functionality :

Measured by its ability to inhibit trypsin cleavage of a fluorogenic peptide substrate, Mca-RPKPVE-Nval-WRK(Dnp)-NH2 (Catalog # ES002 ). The IC50 value is approximately 5.0 nM, as measured under the described conditions.

endotoxin note :

<1.0 EU per 1 µg of the protein by the LAL method.

accessionNumbers :

P01009

applications :

Inhibition Activity

source :

NS0-derived Recombinant Human Serpin A1/alpha-1-Antitrypsin Protein, CF

USD :

388

USD 2023 :

394 USD

alt names :

A1A, A1AT, AATMGC23330, alpha 1-Antitrypsin, alpha 1-Proteinase Inhibitor, Alpha-1 protease inhibitor, Alpha-1-antiproteinase, alpha-1-antitrypsin, antitrypsin), member 1, member 1, PIMGC9222, serine (or cysteine) proteinase inhibitor, clade A (alpha-1 antiproteinase, serine (or cysteine) proteinase inhibitor, clade A, member 1, Serpin A1, serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin)

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 6 months from date of receipt, -20 to -70 °C as supplied. 3 months, -20 to -70 °C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage