Recombinant Human FGFR3 (IIIb) Fc Chimera Protein, CF | R&D Systems 1264-FR product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Human FGFR3 (IIIb) Fc Chimera Protein, CF

catalog :

1264-FR

quantity :

1 mg

price :

4669 USD

citations: 1

Reference
Nakayama T, Mutsuga N, Tosato G. FGF2 posttranscriptionally down-regulates expression of SDF1 in bone marrow stromal cells through FGFR1 IIIc. Blood. 2007;109:1363-72 pubmed

product information

brand :

R&D Systems

master code :

1264-FR

SKU :

1264-FR-01M

product name :

Recombinant Human FGFR3 (IIIb) Fc Chimera Protein, CF

description :

The Recombinant Human FGFR3 (IIIb) Fc Chimera Protein, CF from R&D Systems is derived from NS0. The Recombinant Human FGFR3 (IIIb) Fc Chimera Protein, CF has been validated for the following applications: Bioactivity.

target :

FGFR3

category :

Proteins and Enzymes

unit size :

1 mg

buffer :

Lyophilized from a 0.2 µm filtered solution in PBS.

conjugate :

Unconjugated

purity :

>90%, by SDS-PAGE under reducing conditions and visualized by silver stain

species :

Human

observed molecular weight :

90-100 kDa, reducing conditions

theoretical molecular weight :

65 kDa (monomer)

gene symbol :

FGFR3

details of functionality :

Measured by its ability to inhibit FGF acidic-dependent proliferation of NR6R-3T3 mouse fibroblast cells. The ED50 for this effect is 0.03-0.12 µg/mL.

endotoxin note :

<0.01 EU per 1 µg of the protein by the LAL method.

catalog number base :

1264-FR

accessionNumbers :

NP_001156685

applications :

Bioactivity

source :

Mouse myeloma cell line, NS0-derived human FGF R3 protein Human FGF R3 (IIIb) (Glu23 - Gly377) (Ala361 del) Accession # NP_001156685 IEGRMD Human IgG1 (Pro100 - Lys330) N-terminus C-terminus

2020 USD :

4669

2021 USD :

4669 USD

alt names :

CD333, CEK, EC 2.7.10, FGF R3, fibroblast growth factor receptor 3, HSFGFR3EX, JTK4, JTK4thanatophoric dwarfism

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution.