Recombinant Human IL-17B Protein | R&D Systems 1248-IB-025 product information

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Human IL-17B Protein

catalog :

1248-IB-025

quantity :

25 ug

price :

432 USD

more info or order :

R&D Systems product webpage

citations: 3

Reference
Xiao G, Kumar R, Komuro Y, Burguet J, Kakarla V, Azizkhanian I, et al. IL-17/CXCL5 signaling within the oligovascular niche mediates human and mouse white matter injury. Cell Rep. 2022;41:111848 pubmed publisher
Bie Q, Song H, Chen X, Yang X, Shi S, Zhang L, et al. IL-17B/IL-17RB signaling cascade contributes to self-renewal and tumorigenesis of cancer stem cells by regulating Beclin-1 ubiquitination. Oncogene. 2021;40:2200-2216 pubmed publisher
Goldstein R, Reagan M, Anderson K, Kaplan D, Rosenblatt M. Human bone marrow-derived MSCs can home to orthotopic breast cancer tumors and promote bone metastasis. Cancer Res. 2010;70:10044-50 pubmed publisher

product information

master code :

1248-IB

SKU :

1248-IB-025

product name :

Recombinant Human IL-17B Protein

unit size :

25 ug

description :

The Recombinant Human IL-17B Protein from R&D Systems is derived from E. coli. The Recombinant Human IL-17B Protein has been validated for the following applications: Bioactivity.

target :

IL-17B

category :

Proteins and Enzymes

buffer :

Lyophilized from a 0.2 ╡m filtered solution in NaH2PO4 and NaCl with BSA as a carrier protein.

conjugate :

Unconjugated

purity :

>97%, by SDS-PAGE under reducing conditions and visualized by silver stain

species :

Human

theoretical molecular weight :

18.3 kDa

gene symbol :

IL17B

details of functionality :

Measured by its ability to induce IL-8 secretion by HepG2 human hepatocellular carcinoma cells. Tang, Y. et al . (2011) Clin. Exp. Immunol. 166 :281. The ED50 for this effect is 0.4-2 ╡g/mL.

endotoxin note :

<0.10 EU per 1 ╡g of the protein by the LAL method.

accessionNumbers :

Q9UHF5

applications :

Bioactivity

source long :

E. coli -derived human IL-17B protein Gln21-Phe180, with an N-terminal Met

source short :

E. coli

USD :

432 USD

alt names :

Cytokine Zcyto7, cytokine-like protein ZCYTO7, IL17B, IL-17Binterleukin-17 beta, IL20, IL-20interleukin-17B, interleukin 17B, interleukin 20, Interleukin-20, MGC138900, MGC138901, neuronal interleukin-17 related factor, Neuronal interleukin-17-related factor, NIRF, ZCYTO7interleukin-20

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 3 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage