Recombinant Mouse Galectin-1 Protein | R&D Systems 1245-GA product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Mouse Galectin-1 Protein

catalog :

1245-GA

quantity :

50 ug

price :

339 USD

citations: 10

Reference
Nambiar D, Aguilera T, Cao H, Kwok S, Kong C, Bloomstein J, et al. Galectin-1-driven T cell exclusion in the tumor endothelium promotes immunotherapy resistance. J Clin Invest. 2019;129:5553-5567 pubmed publisher
Lykken J, Horikawa M, Minard Colin V, Kamata M, Miyagaki T, Poe J, et al. Galectin-1 drives lymphoma CD20 immunotherapy resistance: validation of a preclinical system to identify resistance mechanisms. Blood. 2016;127:1886-95 pubmed publisher
Madireddi S, Eun S, Lee S, Nemčovičová I, Mehta A, Zajonc D, et al. Galectin-9 controls the therapeutic activity of 4-1BB-targeting antibodies. J Exp Med. 2014;211:1433-48 pubmed publisher
Lim M, Ahn J, Yi J, Kim M, Son A, Lee S, et al. Induction of galectin-1 by TGF-?1 accelerates fibrosis through enhancing nuclear retention of Smad2. Exp Cell Res. 2014;326:125-35 pubmed publisher
Qu W, Wang Y, Ma J, Tian D, Zhang Q, Pan D, et al. Galectin-1 attenuates astrogliosis-associated injuries and improves recovery of rats following focal cerebral ischemia. J Neurochem. 2011;116:217-26 pubmed publisher
Cedeno Laurent F, Barthel S, Opperman M, Lee D, Clark R, Dimitroff C. Development of a nascent galectin-1 chimeric molecule for studying the role of leukocyte galectin-1 ligands and immune disease modulation. J Immunol. 2010;185:4659-72 pubmed publisher
Tsai C, Chiu Y, Hsu T, Lin I, Hsieh S, Lin K. Galectin-1 promotes immunoglobulin production during plasma cell differentiation. J Immunol. 2008;181:4570-9 pubmed
Plachta N, Annaheim C, Bissiere S, Lin S, Ruegg M, Hoving S, et al. Identification of a lectin causing the degeneration of neuronal processes using engineered embryonic stem cells. Nat Neurosci. 2007;10:712-9 pubmed
Silva Monteiro E, Reis Lorenzato L, Kenji Nihei O, Junqueira M, Rabinovich G, Hsu D, et al. Altered expression of galectin-3 induces cortical thymocyte depletion and premature exit of immature thymocytes during Trypanosoma cruzi infection. Am J Pathol. 2007;170:546-56 pubmed
Endharti A, Zhou Y, Nakashima I, Suzuki H. Galectin-1 supports survival of naive T cells without promoting cell proliferation. Eur J Immunol. 2005;35:86-97 pubmed

product information

brand :

R&D Systems

master code :

1245-GA

SKU :

1245-GA-050

product name :

Recombinant Mouse Galectin-1 Protein

description :

The Recombinant Mouse Galectin-1 Protein from R&D Systems is derived from E. coli. The Recombinant Mouse Galectin-1 Protein has been validated for the following applications: Bioactivity.

target :

Galectin-1

category :

Proteins and Enzymes

unit size :

50 ug

buffer :

Lyophilized from a 0.2 µm filtered solution in PBS, EDTA and DTT with BSA as a carrier protein.

conjugate :

Unconjugated

purity :

>95%, by SDS-PAGE under reducing conditions and visualized by silver stain.

species :

Mouse

theoretical molecular weight :

15 kDa

gene symbol :

Lgals1

details of functionality :

Measured by its ability to agglutinate human red blood cells. Hadari, Y.R. et al . (2000) J. Cell Sci. 113 :2385. The ED50 for this effect is 1-5 µg/mL.

endotoxin note :

<0.10 EU per 1 µg of the protein by the LAL method.

catalog number base :

1245-GA

accessionNumbers :

P16045

applications :

Bioactivity

source :

E. coli -derived mouse Galectin-1 protein Ala2-Glu135

2020 USD :

339

2021 USD :

339 USD

alt names :

14 kDa laminin-binding protein, 14 kDa lectin, Beta-galactoside-binding lectin L-14-I, BHL, DKFZp686E23103, gal-1, GAL1, Galaptin, galectin 1, galectin-1, Galectin1, GBP, HBL, HLBP14, HPL, L-14, Lactose-binding lectin 1, Lectin galactoside-binding soluble 1, lectin, galactoside-binding, soluble, 1, LGALS1, Putative MAPK-activating protein PM12, S-Lac lectin 1

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution.