Recombinant Mouse Galectin-1 Protein | R&D Systems 1245-GA-050 product information

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Mouse Galectin-1 Protein

catalog :

1245-GA-050

quantity :

50 ug

price :

394 USD

more info or order :

R&D Systems product webpage

citations: 12

Reference
Morosi L, Cutine A, Cagnoni A, Manselle Cocco M, Croci D, Merlo J, et al. Control of intestinal inflammation by glycosylation-dependent lectin-driven immunoregulatory circuits. Sci Adv. 2021;7: pubmed publisher
Ge J, Zheng Y, Tsuchida T, Furuya K, Isoda H, Taniguchi H, et al. Hepatic stellate cells contribute to liver regeneration through galectins in hepatic stem cell niche. Stem Cell Res Ther. 2020;11:425 pubmed publisher
Nambiar D, Aguilera T, Cao H, Kwok S, Kong C, Bloomstein J, et al. Galectin-1-driven T cell exclusion in the tumor endothelium promotes immunotherapy resistance. J Clin Invest. 2019;129:5553-5567 pubmed publisher
Lykken J, Horikawa M, Minard Colin V, Kamata M, Miyagaki T, Poe J, et al. Galectin-1 drives lymphoma CD20 immunotherapy resistance: validation of a preclinical system to identify resistance mechanisms. Blood. 2016;127:1886-95 pubmed publisher
Madireddi S, Eun S, Lee S, Nemčovičová I, Mehta A, Zajonc D, et al. Galectin-9 controls the therapeutic activity of 4-1BB-targeting antibodies. J Exp Med. 2014;211:1433-48 pubmed publisher
Lim M, Ahn J, Yi J, Kim M, Son A, Lee S, et al. Induction of galectin-1 by TGF-?1 accelerates fibrosis through enhancing nuclear retention of Smad2. Exp Cell Res. 2014;326:125-35 pubmed publisher
Qu W, Wang Y, Ma J, Tian D, Zhang Q, Pan D, et al. Galectin-1 attenuates astrogliosis-associated injuries and improves recovery of rats following focal cerebral ischemia. J Neurochem. 2011;116:217-26 pubmed publisher
Cedeno Laurent F, Barthel S, Opperman M, Lee D, Clark R, Dimitroff C. Development of a nascent galectin-1 chimeric molecule for studying the role of leukocyte galectin-1 ligands and immune disease modulation. J Immunol. 2010;185:4659-72 pubmed publisher
Tsai C, Chiu Y, Hsu T, Lin I, Hsieh S, Lin K. Galectin-1 promotes immunoglobulin production during plasma cell differentiation. J Immunol. 2008;181:4570-9 pubmed
Plachta N, Annaheim C, Bissiere S, Lin S, Ruegg M, Hoving S, et al. Identification of a lectin causing the degeneration of neuronal processes using engineered embryonic stem cells. Nat Neurosci. 2007;10:712-9 pubmed
Silva Monteiro E, Reis Lorenzato L, Kenji Nihei O, Junqueira M, Rabinovich G, Hsu D, et al. Altered expression of galectin-3 induces cortical thymocyte depletion and premature exit of immature thymocytes during Trypanosoma cruzi infection. Am J Pathol. 2007;170:546-56 pubmed
Endharti A, Zhou Y, Nakashima I, Suzuki H. Galectin-1 supports survival of naive T cells without promoting cell proliferation. Eur J Immunol. 2005;35:86-97 pubmed

product information

brand :

R&D Systems

master code :

1245-GA

SKU :

1245-GA-050

product name :

Recombinant Mouse Galectin-1 Protein

description :

The Recombinant Mouse Galectin-1 Protein from R&D Systems is derived from E. coli. The Recombinant Mouse Galectin-1 Protein has been validated for the following applications: Bioactivity.

target :

Galectin-1

category :

Proteins and Enzymes

sizes available :

50 ug

buffer :

Lyophilized from a 0.2 µm filtered solution in PBS, EDTA and DTT with BSA as a carrier protein.

conjugate :

Unconjugated

purity :

>95%, by SDS-PAGE under reducing conditions and visualized by silver stain.

species :

Mouse

theoretical molecular weight :

15 kDa

gene symbol :

Lgals1

details of functionality :

Measured by its ability to agglutinate human red blood cells. Hadari, Y.R. et al . (2000) J. Cell Sci. 113 :2385. The ED50 for this effect is 1-5 µg/mL.

endotoxin note :

<0.10 EU per 1 µg of the protein by the LAL method.

accessionNumbers :

P16045

applications :

Bioactivity

source :

E. coli-derived Recombinant Mouse Galectin-1 Protein

USD :

388

USD 2023 :

394 USD

alt names :

14 kDa laminin-binding protein, 14 kDa lectin, Beta-galactoside-binding lectin L-14-I, BHL, DKFZp686E23103, gal-1, GAL1, Galaptin, galectin 1, galectin-1, Galectin1, GBP, HBL, HLBP14, HPL, L-14, Lactose-binding lectin 1, Lectin galactoside-binding soluble 1, lectin, galactoside-binding, soluble, 1, LGALS1, Putative MAPK-activating protein PM12, S-Lac lectin 1

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage