product summary
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company name :
R&D Systems
product type :
protein
product name :
Recombinant Mouse Cystatin C Protein, CF
catalog :
1238-PI-010
quantity :
10 ug
price :
432 USD
more info or order :
citations: 2
Reference
Dieterle F, Perentes E, Cordier A, Roth D, Verdes P, Grenet O, et al. Urinary clusterin, cystatin C, beta2-microglobulin and total protein as markers to detect drug-induced kidney injury. Nat Biotechnol. 2010;28:463-9 pubmed publisher
Chang S, Kanasaki K, Gocheva V, Blum G, Harper J, Moses M, et al. VEGF-A induces angiogenesis by perturbing the cathepsin-cysteine protease inhibitor balance in venules, causing basement membrane degradation and mother vessel formation. Cancer Res. 2009;69:4537-44 pubmed publisher
product information
master code :
1238-PI
SKU :
1238-PI-010
product name :
Recombinant Mouse Cystatin C Protein, CF
unit size :
10 ug
description :
The Recombinant Mouse Cystatin C Protein, CF from R&D Systems is derived from NS0. The Recombinant Mouse Cystatin C Protein, CF has been validated for the following applications: Inhibition Activity.
target :
Cystatin C
category :
Proteins and Enzymes
buffer :
Lyophilized from a 0.2 ╡m filtered solution in HEPES and NaCl.
conjugate :
Unconjugated
purity :
>95%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie« Blue Staining.
species :
Mouse
observed molecular weight :
15 kDa, 18 kDa, 20 kDa and 21 kDa, reducing conditions
theoretical molecular weight :
15 kDa
gene symbol :
Cst3
details of functionality :
Measured by its ability to inhibit papain cleavage of a fluorogenic peptide substrate Z-FR-AMC (Catalog # ES009 ). The IC50 value is 10 nM, under the described conditions.
endotoxin note :
<1.0 EU per 1 ╡g of the protein by the LAL method.
accessionNumbers :
P21460
applications :
Inhibition Activity
source long :
Mouse myeloma cell line, NS0-derived mouse Cystatin C protein Met1-Ala140, with a C-terminal 10-His tag
source short :
NS0
USD :
432 USD
alt names :
ARMD11, bA218C14.4 (cystatin C), CST3, cystatin 3, cystatin C, cystatin C (amyloid angiopathy and cerebral hemorrhage), cystatin-3, cystatin-C, Gamma-trace, MGC117328, Neuroendocrine basic polypeptide, Post-gamma-globulin
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 6 months from date of receipt, -20 to -70 ░C as supplied. 3 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.