Recombinant Human IL-17C Protein | R&D Systems 1234-IL-025 product information

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Human IL-17C Protein

catalog :

1234-IL-025

quantity :

25 ug

price :

423 USD

more info or order :

R&D Systems product webpage

citations: 4

Reference
Xiao G, Kumar R, Komuro Y, Burguet J, Kakarla V, Azizkhanian I, et al. IL-17/CXCL5 signaling within the oligovascular niche mediates human and mouse white matter injury. Cell Rep. 2022;41:111848 pubmed publisher
Ritzmann F, Jungnickel C, Vella G, Kamyschnikow A, Herr C, Li D, et al. IL-17C-mediated innate inflammation decreases the response to PD-1 blockade in a model of Kras-driven lung cancer. Sci Rep. 2019;9:10353 pubmed publisher
Johnston A, Fritz Y, Dawes S, Diaconu D, Al Attar P, Guzman A, et al. Keratinocyte overexpression of IL-17C promotes psoriasiform skin inflammation. J Immunol. 2013;190:2252-62 pubmed publisher
Wilson T, Fridlyand J, Yan Y, Penuel E, Burton L, Chan E, et al. Widespread potential for growth-factor-driven resistance to anticancer kinase inhibitors. Nature. 2012;487:505-9 pubmed publisher

product information

brand :

R&D Systems, a Bio-Techne Brand

catalog number base :

1234-IL

SKU :

1234-IL-025

product name :

Recombinant Human IL-17C Protein

Description :

The Recombinant Human IL-17C Protein from R&D Systems is derived from E. coli. The Recombinant Human IL-17C Protein has been validated for the following applications: Binding Activity.

target :

IL-17C

category :

Proteins and Enzymes

unit size :

25 ug

buffer :

Lyophilized from a 0.2 µm filtered solution in Acetonitrile and TFA with BSA as a carrier protein.

conjugate :

Unconjugated

purity :

>95%, by SDS-PAGE under reducing conditions and visualized by silver stain

species :

Human

theoretical molecular weight :

19.8 kDa (monomer)

gene symbol :

IL17C

details of functionality :

Measured by its binding ability in a functional ELISA. When Recombinant Human IL-17 RE Fc Chimera (Catalog # 8358-MR ) is immobilized at 0.25 µg/mL (100 µL/well), the concentration of Recombinant Human IL-17C that produces 50% of the optimal binding response is 1.5-7.5 ng/mL.

endotoxin note :

<0.10 EU per 1 µg of the protein by the LAL method.

accessionNumbers :

Q9P0M4.1

applications :

Binding Activity

source :

E. coli-derived Recombinant Human IL-17C Protein

USD :

423 USD

alt names :

CX2, Cytokine CX2, IL17C, IL-17CMGC126884, interleukin 17C, interleukin-17C, MGC138401

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage