Recombinant Human Galectin-4 Protein, CF | R&D Systems 1227-GA-050/CF product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Human Galectin-4 Protein, CF

catalog :

1227-GA-050/CF

quantity :

50 ug

price :

456 USD

citations: 3

Reference
Terävä J, Tiainen L, Lamminmaki U, Kellokumpu Lehtinen P, Pettersson K, Gidwani K. Lectin nanoparticle assays for detecting breast cancer-associated glycovariants of cancer antigen 15-3 (CA15-3) in human plasma. PLoS ONE. 2019;14:e0219480 pubmed publisher
Madireddi S, Eun S, Lee S, Nemčovičová I, Mehta A, Zajonc D, et al. Galectin-9 controls the therapeutic activity of 4-1BB-targeting antibodies. J Exp Med. 2014;211:1433-48 pubmed publisher
Paclik D, Danese S, Berndt U, Wiedenmann B, Dignass A, Sturm A. Galectin-4 controls intestinal inflammation by selective regulation of peripheral and mucosal T cell apoptosis and cell cycle. PLoS ONE. 2008;3:e2629 pubmed publisher

product information

master code :

1227-GA/CF

SKU :

1227-GA-050/CF

product name :

Recombinant Human Galectin-4 Protein, CF

unit size :

50 ug

description :

The Recombinant Human Galectin-4 Protein, CF from R&D Systems is derived from E. coli. The Recombinant Human Galectin-4 Protein, CF has been validated for the following applications: Bioactivity, Binding Activity.

target :

Galectin-4

category :

Proteins and Enzymes

buffer :

Lyophilized from a 0.2 ╡m filtered solution in HEPES, NaCl, TCEP, PEG and Trehalose.

conjugate :

Unconjugated

purity :

>95%, by SDS-PAGE under reducing conditions and visualized by silver stain.

species :

Human

theoretical molecular weight :

36 kDa

gene symbol :

LGALS4

details of functionality :

Measured by its ability to agglutinate human red blood cells. Hadari, Y.R. et al . (2000) J. Cell Sci. 113 :2385. The ED50 for this effect is 2-10 ╡g/mL. Measured by its binding activity in a functional ELISA. Ideo, H. et al . (2005) J. Biol. Chem. 280 :4730. Recombinant Human Galectin-4 can bind Recombinant Human CEACAM-5/CD66e (Catalog # 4128-CM ) with an estimated Kd 4nM.

endotoxin note :

<0.10 EU per 1 ╡g of the protein by the LAL method.

accessionNumbers :

P56470

applications :

Bioactivity, Binding Activity

source long :

E. coli -derived human Galectin-4 protein Ala2-Ile323

source short :

E. coli

USD :

456 USD

alt names :

Antigen NY-CO-27, gal-4, GAL4, galectin 4, galectin-4, Galectin4, L-36 lactose-binding protein, L36LBP, Lactose-binding lectin 4, lectin, galactoside-binding, soluble, 4, LGALS4

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 3 months, -20 to -70 ░C under sterile conditions after reconstitution.