Recombinant Human KIR3DL1 Fc Chimera Protein, CF | R&D Systems 1225-KR-050 product information

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Human KIR3DL1 Fc Chimera Protein, CF

catalog :

1225-KR-050

quantity :

50 ug

price :

518 USD

more info or order :

R&D Systems product webpage

citations: 4

Reference
Fittje P, H x153 lzemer A, Garcia Beltran W, Vollmers S, Niehrs A, Hagemann K, et al. HIV-1 Nef-mediated downregulation of CD155 results in viral restriction by KIR2DL5+ NK cells. PLoS Pathog. 2022;18:e1010572 pubmed publisher
Ambrosio A, Bavia L, Borges B, Hiraiwa P, Pietsch J, Ribeiro M, et al. Novel findings on the role of ficolins and colectins in the innate response against Leishmania braziliensis. Acta Trop. 2020;212:105673 pubmed publisher
Wauquier N, Petitdemange C, Tarantino N, Maucourant C, Coomber M, Lungay V, et al. HLA-C-restricted viral epitopes are associated with an escape mechanism from KIR2DL2+ NK cells in Lassa virus infection. EBioMedicine. 2019;40:605-613 pubmed publisher
Cifaldi L, Romania P, Falco M, Lorenzi S, Meazza R, Petrini S, et al. ERAP1 regulates natural killer cell function by controlling the engagement of inhibitory receptors. Cancer Res. 2015;75:824-34 pubmed publisher

product information

brand :

R&D Systems

master code :

1225-KR

SKU :

1225-KR-050

product name :

Recombinant Human KIR3DL1 Fc Chimera Protein, CF

unit size :

50 ug

seo description :

The Recombinant Human KIR3DL1 Fc Chimera Protein, CF from R&D Systems is derived from NS0. The Recombinant Human KIR3DL1 Fc Chimera Protein, CF has been validated for the following applications: Binding Activity.

target :

KIR3DL1

category :

Proteins and Enzymes

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS.

conjugate :

Unconjugated

dilution :

Binding Activity

purity :

>95%, by SDS-PAGE under reducing conditions and visualized by silver stain.

species :

Human

observed molecular weight :

70-90 kDa, reducing conditions

theoretical molecular weight :

61.7 kDa (monomer)

gene symbol :

KIR3DL1

details of functionality :

Measured by its ability to bind HLA on MDA-MB-231 human breast cancer cells. The ED50 for this effect is 0.02-0.12 ╡g/mL. Optimal dilutions should be determined by each laboratory for each application.

endotoxin note :

<0.01 EU per 1 ╡g of the protein by the LAL method.

top caption :

Recombinant Human KIR3DL1 Fc Chimera Protein Bioactivity

accessionNumbers :

P43629

applications :

Binding Activity

source :

NS0-derived Recombinant Human KIR3DL1 Fc Chimera Protein, CF

USD :

518 USD

alt names :

AMB11, CD158 antigen-like family member E, CD158E, CD158e antigen, CD158e1, CD158e1/2, CD158e2, cl-11, cl-2, HLA-BW4-specific inhibitory NK cell receptor, killer cell immunoglobulin-like receptor 3DL1, killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail1,nkat3, killer Ig receptor, KIR antigen 3DL1, KIR3DL1/S1, KIR3DS1, MGC119726, MGC119728, MGC126589, MGC126591, MHC class I NK cell receptor, Natural killer-associated transcript 3, Nkat3, NKAT-3, NKAT3KIR, NKB1, NKB1B, NKB1CD158E1, NK-receptor, p70 killer cell inhibitory receptor, p70 natural killer cell receptor clones CL-2/CL-11, p70 NK receptor CL-2/CL-11

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 3 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage