Recombinant Mouse CD40/TNFRSF5 Fc Chimera Protein, CF | R&D Systems 1215-CD-050 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Mouse CD40/TNFRSF5 Fc Chimera Protein, CF

catalog :

1215-CD-050

quantity :

50 ug

price :

443 USD

citations: 5

Reference
Park H, Kim K, Kim J, Kim S, Oh Y, Kang M, et al. Improved safety of chimeric antigen receptor T cells indirectly targeting antigens via switchable adapters. Nat Commun. 2024;15:9917 pubmed publisher
Poels K, Schreurs M, Jansen M, Vugts D, Seijkens T, van Dongen G, et al. Immuno-PET Imaging of Atherosclerotic Plaques with [89Zr]Zr-Anti-CD40 mAb-Proof of Concept. Biology (Basel). 2022;11: pubmed publisher
Li Q, Cao Q, Wang C, Nguyen H, Wang X, Zheng G, et al. Dendritic cell-targeted CD40 DNA vaccine suppresses Th17 and ameliorates progression of experimental autoimmune glomerulonephritis. J Leukoc Biol. 2019;105:809-819 pubmed publisher
Hong C, Qiu X, Li Y, Huang Q, Zhong Z, Zhang Y, et al. Functional analysis of recombinant calreticulin fragment 39-272: implications for immunobiological activities of calreticulin in health and disease. J Immunol. 2010;185:4561-9 pubmed publisher
Akiyama T, Shimo Y, Yanai H, Qin J, Ohshima D, Maruyama Y, et al. The tumor necrosis factor family receptors RANK and CD40 cooperatively establish the thymic medullary microenvironment and self-tolerance. Immunity. 2008;29:423-37 pubmed publisher

product information

master code :

1215-CD

SKU :

1215-CD-050

product name :

Recombinant Mouse CD40/TNFRSF5 Fc Chimera Protein, CF

unit size :

50 ug

description :

The Recombinant Mouse CD40/TNFRSF5 Fc Chimera Protein, CF from R&D Systems is derived from NS0. The Recombinant Mouse CD40/TNFRSF5 Fc Chimera Protein, CF has been validated for the following applications: Bioactivity.

target :

CD40/TNFRSF5

category :

Proteins and Enzymes

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS.

conjugate :

Unconjugated

purity :

>90%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie« Blue Staining.

species :

Mouse

observed molecular weight :

58-61 kDa, reducing conditions

theoretical molecular weight :

46 kDa (monomer)

gene symbol :

Cd40

details of functionality :

Measured by its binding ability in a functional ELISA. When Recombinant Mouse CD40/TNFRSF5 Fc Chimera is immobilized at 1 ╡g/mL (100 ╡L/well), the concentration of Recombinant Mouse CD40 Ligand/TNFSF5 (Catalog # 8230-CL ) that produces 50% optimal binding is found to be 100-600 ng/mL.

endotoxin note :

<0.10 EU per 1 ╡g of the protein by the LAL method.

accessionNumbers :

P27512

applications :

Bioactivity

source long :

Mouse myeloma cell line, NS0-derived mouse CD40/TNFRSF5 protein Mouse CD40 (Val24-Arg193) Accession # P27512 DIEGRMD Human IgG1 (Pro100-Lys330) 6-His tag N-terminus C-terminus

source short :

NS0

USD :

443 USD

alt names :

B cell surface antigen CD40, B-cell surface antigen CD40, Bp50B cell-associated molecule, CD40, CD40 antigen, CD40 molecule, TNF receptor superfamily member 5, CD40 type II isoform, CD40L receptor, CDw40, MGC9013, nerve growth factor receptor-related B-lymphocyte activation molecule, p50, TNFRSF5, TNFRSF5CD40 antigen (TNF receptor superfamily member 5), tumor necrosis factor receptor superfamily member 5, tumor necrosis factor receptor superfamily, member 5

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 3 months, -20 to -70 ░C under sterile conditions after reconstitution.