Recombinant Mouse JAM-C Fc Chimera Protein, CF | R&D Systems 1213-J3-050 product information

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Mouse JAM-C Fc Chimera Protein, CF

catalog :

1213-J3-050

quantity :

50 ug

price :

432 USD

more info or order :

R&D Systems product webpage

citations: 5

Reference
Czabanka M, Petrilli L, Elvers Hornung S, Bieback K, Albert Imhof B, Vajkoczy P, et al. Junctional Adhesion Molecule-C Mediates the Recruitment of Embryonic-Endothelial Progenitor Cells to the Perivascular Niche during Tumor Angiogenesis. Int J Mol Sci. 2020;21: pubmed publisher
Radulović V, van der Garde M, Koide S, Sigurdsson V, Lang S, Kaneko S, et al. Junctional Adhesion Molecule 2 Represents a Subset of Hematopoietic Stem Cells with Enhanced Potential for T Lymphopoiesis. Cell Rep. 2019;27:2826-2836.e5 pubmed publisher
Hintermann E, Bayer M, Ehser J, Aurrand Lions M, Pfeilschifter J, Imhof B, et al. Murine junctional adhesion molecules JAM-B and JAM-C mediate endothelial and stellate cell interactions during hepatic fibrosis. Cell Adh Migr. 2016;10:419-33 pubmed publisher
Su R, Jia B, Ni H, Lei W, Yue S, Feng X, et al. Junctional adhesion molecule 2 mediates the interaction between hatched blastocyst and luminal epithelium: induction by progesterone and LIF. PLoS ONE. 2012;7:e34325 pubmed publisher
Arcangeli M, Frontera V, Bardin F, Obrados E, Adams S, Chabannon C, et al. JAM-B regulates maintenance of hematopoietic stem cells in the bone marrow. Blood. 2011;118:4609-19 pubmed publisher

product information

master code :

1213-J3

SKU :

1213-J3-050

product name :

Recombinant Mouse JAM-C Fc Chimera Protein, CF

unit size :

50 ug

description :

The Recombinant Mouse JAM-C Fc Chimera Protein, CF from R&D Systems is derived from NS0. The Recombinant Mouse JAM-C Fc Chimera Protein, CF has been validated for the following applications: Bioactivity.

target :

JAM-C

category :

Proteins and Enzymes

buffer :

Lyophilized from a 0.2 ╡m filtered solution in Tris-Citrate and NaCl.

conjugate :

Unconjugated

purity :

>95%, by SDS-PAGE under reducing conditions and visualized by silver stain

species :

Mouse

observed molecular weight :

64 kDa, reducing conditions

theoretical molecular weight :

50 kDa (monomer)

gene symbol :

Jam3

details of functionality :

Measured by its ability to inhibit the adhesion of J45.01 human acute lymphoblastic leukemia T lymphocytes on immobilized JAM-2 (VE-JAM)/Fc Chimera. The ED50 for this effect is 0.1-0.5 ╡g/mL in the presence of 1 x 105 cells/well. Each well was coated with 100 ╡L of a 0.2 ╡g/mL solution of rhJAM-2 (VE-JAM)/Fc Chimera.

endotoxin note :

<0.10 EU per 1 ╡g of the protein by the LAL method.

accessionNumbers :

Q9D8B7

applications :

Bioactivity

source long :

Mouse myeloma cell line, NS0-derived mouse JAM-C protein Mouse JAM-C (Val32 - Asn241) Accession # Q9D8B7 IEGRMD Human IgG1 (Pro100 - Lys330) N-terminus C-terminus

source short :

NS0

USD :

432 USD

alt names :

CD323, JAM-2, JAM3, JAMC, JAM-CFLJ14529, junctional adhesion molecule 3JAM-3, junctional adhesion molecule C

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 3 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage