Recombinant Mouse IFN-alpha 4 (Mammalian) Protein | R&D Systems 12115-1 product information

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Mouse IFN-alpha 4 (Mammalian) Protein

catalog :

12115-1

quantity :

100000 UN

price :

556 USD

more info or order :

R&D Systems product webpage

citations: 3

Reference
Cao Y, Wu J, Hu Y, Chai Y, Song J, Duan J, et al. Virus-induced lncRNA-BTX allows viral replication by regulating intracellular translocation of DHX9 and ILF3 to induce innate escape. Cell Rep. 2023;42:113262 pubmed publisher
Xu J, Wang P, Li Z, Li Z, Han D, Wen M, et al. IRF3-binding lncRNA-ISIR strengthens interferon production in viral infection and autoinflammation. Cell Rep. 2021;37:109926 pubmed publisher
Hu M, Xie X, Yang Q, Liao C, Ye W, Lin H, et al. TRIM38 Negatively Regulates TLR3/4-Mediated Innate Immune and Inflammatory Responses by Two Sequential and Distinct Mechanisms. J Immunol. 2015;195:4415-25 pubmed publisher

product information

brand :

R&D Systems

master code :

12115-1

SKU :

12115-1

product name :

Recombinant Mouse IFN-alpha 4 (Mammalian) Protein

unit size :

100000 UN

seo description :

The Recombinant Mouse IFN-alpha 4 (Mammalian) Protein has been validated for the following applications: Bioactivity.

target :

IFN-alpha 4

category :

Proteins and Enzymes

buffer :

Phosphate buffered saline (PBS) containing 0.1% bovine serum albumin (BSA)

conjugate :

Unconjugated

dilution :

Bioactivity

species :

Mouse

theoretical molecular weight :

19.5 kDa

gene symbol :

Ifna4

details of functionality :

Interferon was titrated with the use of the cytopathic effect inhibition assay as described [Familletti et al. (1981) "A Convenience and Rapid Cytopathic Effect Inhibition Assay for Interferon," in Methods in Enzymology , Vol. 78 (S. Pestka, ed.), Academic Press, New York, 387-394] with the exception that EMCV rather than VSV was used as the challenge. The activity was determined relative to a lab standard of Mu-IFN-alpha A which was calibrated to the NIH Murine IFN-alpha standard (Ga02-901-511). Mouse (L929/EMCV) in this assay the EC50 for IFN is ~5 U/ml. Lot Activity was derived from multiple determinations in the above assay. Please note that IFN assays vary between labs and assay systems [Meager et al (2001). J. Immunol. Meth. 257:17. Meager and Das (2005) J. Immunol Meth. 306:1]

endotoxin note :

<1.0 EU per 1 ╡g of the protein by the LAL method.

accessionNumbers :

NM_010504

applications :

Bioactivity

extended description :

A New rmIFN-alpha 4 is Available! It has lower endotoxin specifications, is made in-house, and is priced competitively!

USD :

556 USD

product details :

A New rmIFN-alpha 4 is Available! It has lower endotoxin specifications, is made in-house, and is priced competitively!

alt names :

IFNA4, IFNalpha 4, IFN-alpha-4, IFN-alpha4a, INFA4, interferon alpha-4, Interferon alpha-4B, Interferon alpha-76, Interferon alpha-M1, interferon, alpha 4, MGC142200

storage :

Store the unopened product at -20 to -70 ░C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.

more info or order :

R&D Systems product webpage