product summary
Loading...
company name :
R&D Systems
product type :
protein
product name :
Recombinant Mouse IFN-alpha A Protein
catalog :
12100-1
quantity :
100000 UN
price :
660 USD
more info or order :
citations: 25
Reference
Gervais A, Le Floc h C, Le Voyer T, Bizien L, Bohlen J, Celmeli F, et al. A sensitive assay for measuring whole-blood responses to type I IFNs. Proc Natl Acad Sci U S A. 2024;121:e2402983121 pubmed publisher
Yang L, Chen S, Zhao Q, Pan C, Peng L, Han Y, et al. Histone deacetylase 3 contributes to the antiviral innate immunity of macrophages by interacting with FOXK1 to regulate STAT1/2 transcription. Cell Rep. 2022;38:110302 pubmed publisher
Hur J, Frost G, Wu X, Crump C, Pan S, Wong E, et al. The innate immunity protein IFITM3 modulates γ-secretase in Alzheimer's disease. Nature. 2020;586:735-740 pubmed publisher
Ge C, Monk I, Pizzolla A, Wang N, Bedford J, Stinear T, et al. Bystander Activation of Pulmonary Trm Cells Attenuates the Severity of Bacterial Pneumonia by Enhancing Neutrophil Recruitment. Cell Rep. 2019;29:4236-4244.e3 pubmed publisher
Haruwaka K, Ikegami A, Tachibana Y, Ohno N, Konishi H, Hashimoto A, et al. Dual microglia effects on blood brain barrier permeability induced by systemic inflammation. Nat Commun. 2019;10:5816 pubmed publisher
Zhang Y, Thery F, Wu N, Luhmann E, Dussurget O, Foecke M, et al. The in vivo ISGylome links ISG15 to metabolic pathways and autophagy upon Listeria monocytogenes infection. Nat Commun. 2019;10:5383 pubmed publisher
Gal Oz S, Maier B, Yoshida H, Seddu K, Elbaz N, Czysz C, et al. ImmGen report: sexual dimorphism in the immune system transcriptome. Nat Commun. 2019;10:4295 pubmed publisher
Li W, Feng G, Gauthier J, Lokshina I, Higashikubo R, Evans S, et al. Ferroptotic cell death and TLR4/Trif signaling initiate neutrophil recruitment after heart transplantation. J Clin Invest. 2019;129:2293-2304 pubmed publisher
Stier M, Goleniewska K, Cephus J, Newcomb D, Sherrill T, Boyd K, et al. STAT1 Represses Cytokine-Producing Group 2 and Group 3 Innate Lymphoid Cells during Viral Infection. J Immunol. 2017;199:510-519 pubmed publisher
Moodley D, Yoshida H, Mostafavi S, Asinovski N, Ortiz Lopez A, Symanowicz P, et al. Network pharmacology of JAK inhibitors. Proc Natl Acad Sci U S A. 2016;113:9852-7 pubmed publisher
Ananth A, Tai L, Lansdell C, Alkayyal A, Baxter K, Angka L, et al. Surgical Stress Abrogates Pre-Existing Protective T Cell Mediated Anti-Tumor Immunity Leading to Postoperative Cancer Recurrence. PLoS ONE. 2016;11:e0155947 pubmed publisher
Shou P, Chen Q, Jiang J, Xu C, Zhang J, Zheng C, et al. Type I interferons exert anti-tumor effect via reversing immunosuppression mediated by mesenchymal stromal cells. Oncogene. 2016;35:5953-5962 pubmed publisher
Labzin L, Schmidt S, Masters S, Beyer M, Krebs W, Klee K, et al. ATF3 Is a Key Regulator of Macrophage IFN Responses. J Immunol. 2015;195:4446-55 pubmed publisher
Kuriakose T, Tripp R, Watford W. Tumor Progression Locus 2 Promotes Induction of IFNλ, Interferon Stimulated Genes and Antigen-Specific CD8+ T Cell Responses and Protects against Influenza Virus. PLoS Pathog. 2015;11:e1005038 pubmed publisher
Hong B, Li H, Lu Y, Zhang M, Zheng Y, Qian J, et al. USP18 is crucial for IFN-?-mediated inhibition of B16 melanoma tumorigenesis and antitumor immunity. Mol Cancer. 2014;13:132 pubmed publisher
Yao H, Goldman D, Nechiporuk T, Kawane S, McWeeney S, Tyner J, et al. Corepressor Rcor1 is essential for murine erythropoiesis. Blood. 2014;123:3175-84 pubmed publisher
Bezbradica J, Rosenstein R, DeMarco R, Brodsky I, Medzhitov R. A role for the ITAM signaling module in specifying cytokine-receptor functions. Nat Immunol. 2014;15:333-42 pubmed publisher
Bosmann M, Strobl B, Kichler N, Rigler D, Grailer J, Pache F, et al. Tyrosine kinase 2 promotes sepsis-associated lethality by facilitating production of interleukin-27. J Leukoc Biol. 2014;96:123-31 pubmed publisher
Lu B, Antoine D, Kwan K, Lundbäck P, Wähämaa H, Schierbeck H, et al. JAK/STAT1 signaling promotes HMGB1 hyperacetylation and nuclear translocation. Proc Natl Acad Sci U S A. 2014;111:3068-73 pubmed publisher
Pereira Lopes S, Celhar T, Sans Fons G, Serra M, Fairhurst A, Lloberas J, et al. The exonuclease Trex1 restrains macrophage proinflammatory activation. J Immunol. 2013;191:6128-35 pubmed publisher
Kerenyi M, Shao Z, Hsu Y, Guo G, Luc S, O Brien K, et al. Histone demethylase Lsd1 represses hematopoietic stem and progenitor cell signatures during blood cell maturation. elife. 2013;2:e00633 pubmed publisher
Freeman B, Hammarlund E, Raué H, Slifka M. Regulation of innate CD8+ T-cell activation mediated by cytokines. Proc Natl Acad Sci U S A. 2012;109:9971-6 pubmed publisher
Yamada A, Suzuki D, Miyazono A, Oshima K, Kamiya A, Zhao B, et al. IFN-gamma down-regulates Secretoglobin 3A1 gene expression. Biochem Biophys Res Commun. 2009;379:964-8 pubmed publisher
Guo B, Chang E, Cheng G. The type I IFN induction pathway constrains Th17-mediated autoimmune inflammation in mice. J Clin Invest. 2008;118:1680-90 pubmed publisher
Best S, Morris K, Shannon J, Robertson S, Mitzel D, Park G, et al. Inhibition of interferon-stimulated JAK-STAT signaling by a tick-borne flavivirus and identification of NS5 as an interferon antagonist. J Virol. 2005;79:12828-39 pubmed
product information
brand :
R&D Systems
master code :
12100-1
SKU :
12100-1
product name :
Recombinant Mouse IFN-alpha A Protein
unit size :
100000 UN
seo description :
The Recombinant Mouse IFN-alpha A Protein from R&D Systems is derived from E. coli.
target :
IFN-alpha 2/IFNA2
category :
Proteins and Enzymes
conjugate :
Unconjugated
species :
Mouse
accessionNumbers :
NP_996753
source :
E. coli-derived Recombinant Mouse IFN-alpha A Protein
extended description :
A New rmIFN-alpha A is Available! It is mammalian cell derived, has lower endotoxin specifications, is made in-house, and is priced competitively!
USD :
660 USD
product details :
A New rmIFN-alpha A is Available! It is mammalian cell derived, has lower endotoxin specifications, is made in-house, and is priced competitively!
alt names :
alpha-2a interferon, Ifa2, IFNA, IFNA2, IFNA2a, IFNA2b, IFNA2c, IFNAA, IFNalpha 2, IFN-alpha-2, IFN-alphaA, INFA2, interferon alpha 2b, interferon alpha A, interferon alpha-2, Interferon alpha-A, interferon, alpha 2, LeIF A, MGC125764, MGC125765
storage :
Store the unopened product at -70 ░C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.
more info or order :
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.