Recombinant Human Growth Hormone R (GHR) Fc Chimera, CF | R&D Systems 1210-GR-050 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Human Growth Hormone R (GHR) Fc Chimera, CF

catalog :

1210-GR-050

quantity :

50 ug

price :

456 USD

citations: 2

Reference
Basu R, Brody R, Sandbhor U, Kulkarni P, Davis E, Swegan D, et al. Structure and function of a dual antagonist of the human growth hormone and prolactin receptors with site-specific PEG conjugates. J Biol Chem. 2023;299:105030 pubmed publisher
Villemagne D, Jackson R, Douthwaite J. Highly efficient ribosome display selection by use of purified components for in vitro translation. J Immunol Methods. 2006;313:140-8 pubmed

product information

master code :

1210-GR

SKU :

1210-GR-050

product name :

Recombinant Human Growth Hormone R (GHR) Fc Chimera, CF

unit size :

50 ug

description :

The Recombinant Human Growth Hormone R (GHR) Fc Chimera, CF from R&D Systems is derived from NS0. The Recombinant Human Growth Hormone R (GHR) Fc Chimera, CF has been validated for the following applications: Bioactivity.

target :

Growth Hormone R/GHR

category :

Proteins and Enzymes

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS.

conjugate :

Unconjugated

purity :

>90%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie« Blue Staining.

species :

Human

observed molecular weight :

75-90 kDa, reducing conditions

theoretical molecular weight :

54 kDa (monomer)

gene symbol :

GHR

details of functionality :

Measured by its ability to inhibit GH-induced proliferation of Nb2-11 rat lymphoma cells. Gout, P.W. et al . (1980) Cancer Res. 40 :2433. The ED50 for this effect is 0.4-2.0 ng/mL in the presence of 0.2 ng/mL of rhGH.

endotoxin note :

<0.01 EU per 1 ╡g of the protein by the LAL method.

accessionNumbers :

P10912

applications :

Bioactivity

source long :

Mouse myeloma cell line, NS0-derived human Growth Hormone R/GHR protein Human GHR (Ala27-Tyr264) Accession # P10912 IEGRMD Human IgG1 (Pro100-Lys330) N-terminus C-terminus

source short :

NS0

USD :

456 USD

alt names :

GH receptor, GHBP, GHR, growth hormone binding protein, growth hormone receptor, serum binding protein, Somatotropin receptor

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 3 months, -20 to -70 ░C under sterile conditions after reconstitution.