Recombinant Human FGF-3 Protein | R&D Systems 1206-F3 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Human FGF-3 Protein

catalog :

1206-F3

quantity :

25 ug

price :

369 USD

citations: 8

Reference
Lahlou H, Lopez Juarez A, Fontbonne A, Nivet E, Zine A. Modeling human early otic sensory cell development with induced pluripotent stem cells. PLoS ONE. 2018;13:e0198954 pubmed publisher
Zhong C, Chen Z, Luo X, Wang C, Jiang H, Shao J, et al. Barhl1 is required for the differentiation of inner ear hair cell-like cells from mouse embryonic stem cells. Int J Biochem Cell Biol. 2018;96:79-89 pubmed publisher
Hanker A, Garrett J, Estrada M, Moore P, Ericsson P, Koch J, et al. HER2-Overexpressing Breast Cancers Amplify FGFR Signaling upon Acquisition of Resistance to Dual Therapeutic Blockade of HER2. Clin Cancer Res. 2017;23:4323-4334 pubmed publisher
Dalle Nogare D, Somers K, Rao S, Matsuda M, Reichman Fried M, Raz E, et al. Leading and trailing cells cooperate in collective migration of the zebrafish posterior lateral line primordium. Development. 2014;141:3188-96 pubmed publisher
Kanehira M, Kikuchi T, Santoso A, Tode N, Hirano T, Ohkouchi S, et al. Human marrow stromal cells downsize the stem cell fraction of lung cancers by fibroblast growth factor 10. Mol Cell Biol. 2014;34:2848-56 pubmed publisher
Mann Z, Thiede B, Chang W, Shin J, May Simera H, Lovett M, et al. A gradient of Bmp7 specifies the tonotopic axis in the developing inner ear. Nat Commun. 2014;5:3839 pubmed publisher
Tomlinson D, Knowles M. Altered splicing of FGFR1 is associated with high tumor grade and stage and leads to increased sensitivity to FGF1 in bladder cancer. Am J Pathol. 2010;177:2379-86 pubmed publisher
Yamamoto S, Fukumoto E, Yoshizaki K, Iwamoto T, Yamada A, Tanaka K, et al. Platelet-derived growth factor receptor regulates salivary gland morphogenesis via fibroblast growth factor expression. J Biol Chem. 2008;283:23139-49 pubmed publisher

product information

brand :

R&D Systems

master code :

1206-F3

SKU :

1206-F3-025

product name :

Recombinant Human FGF-3 Protein

description :

The Recombinant Human FGF-3 Protein from R&D Systems is derived from E. coli. The Recombinant Human FGF-3 Protein has been validated for the following applications: Bioactivity.

target :

FGF-3

category :

Proteins and Enzymes

unit size :

25 ug

buffer :

Lyophilized from a 0.2 µm filtered solution in MOPS, Na2SO4 and EDTA with BSA as a carrier protein.

conjugate :

Unconjugated

purity :

>97%, by SDS-PAGE under reducing conditions and visualized by silver stain.

species :

Human

theoretical molecular weight :

21.1 kDa

gene symbol :

FGF3

details of functionality :

Measured in a cell proliferation assay using NR6R-3T3 mouse fibroblast cells. Rizzino, A. et al . (1988) Cancer Res. 48 :4266; Thomas, K. et al . (1987) Methods Enzymol. 147 :120. The ED50 for this effect is 0.02-0.1 µg/mL in the presence of 1 µg/mL of heparin.

endotoxin note :

<0.10 EU per 1 µg of the protein by the LAL method.

catalog number base :

1206-F3

accessionNumbers :

NP_005238

applications :

Bioactivity

source :

E. coli -derived human FGF-3 protein Asp28-Arg212, with an N-terminal Met

2020 USD :

349

2021 USD :

369 USD

alt names :

FGF3, fibroblast growth factor 3, fibroblast growth factor 3 (murine mammary tumor virus integration site (v-int-2) oncogene homolog), HBGF-3, Hst, INT-2, mouse, oncogene INT2

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution.