Recombinant Human FGF-3 Protein, CF | R&D Systems 1206-F3-025/CF product information

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Human FGF-3 Protein, CF

catalog :

1206-F3-025/CF

quantity :

25 ug

price :

480 USD

more info or order :

R&D Systems product webpage

citations: 12

Reference
Saeki T, Yoshimatsu S, Ishikawa M, Hon C, Koya I, Shibata S, et al. Critical roles of FGF, RA, and WNT signalling in the development of the human otic placode and subsequent lineages in a dish. Regen Ther. 2022;20:165-186 pubmed publisher
Cui L, Zheng J, Zhao Q, Chen J, Liu H, Peng G, et al. Mutations of MAP1B encoding a microtubule-associated phosphoprotein cause sensorineural hearing loss. JCI Insight. 2020;5: pubmed publisher
Boddy S, Romero Guevara R, Ji A, Unger C, Corns L, Marcotti W, et al. Generation of Otic Lineages from Integration-Free Human-Induced Pluripotent Stem Cells Reprogrammed by mRNAs. Stem Cells Int. 2020;2020:3692937 pubmed publisher
Westphal S, Gantert T, Kless C, Hüttinger K, Klingenspor M, Fromme T. Fibroblast growth factor 8b induces uncoupling protein 1 expression in epididymal white preadipocytes. Sci Rep. 2019;9:8470 pubmed publisher
Lahlou H, Lopez Juarez A, Fontbonne A, Nivet E, Zine A. Modeling human early otic sensory cell development with induced pluripotent stem cells. PLoS ONE. 2018;13:e0198954 pubmed publisher
Zhong C, Chen Z, Luo X, Wang C, Jiang H, Shao J, et al. Barhl1 is required for the differentiation of inner ear hair cell-like cells from mouse embryonic stem cells. Int J Biochem Cell Biol. 2018;96:79-89 pubmed publisher
Hanker A, Garrett J, Estrada M, Moore P, Ericsson P, Koch J, et al. HER2-Overexpressing Breast Cancers Amplify FGFR Signaling upon Acquisition of Resistance to Dual Therapeutic Blockade of HER2. Clin Cancer Res. 2017;23:4323-4334 pubmed publisher
Dalle Nogare D, Somers K, Rao S, Matsuda M, Reichman Fried M, Raz E, et al. Leading and trailing cells cooperate in collective migration of the zebrafish posterior lateral line primordium. Development. 2014;141:3188-96 pubmed publisher
Kanehira M, Kikuchi T, Santoso A, Tode N, Hirano T, Ohkouchi S, et al. Human marrow stromal cells downsize the stem cell fraction of lung cancers by fibroblast growth factor 10. Mol Cell Biol. 2014;34:2848-56 pubmed publisher
Mann Z, Thiede B, Chang W, Shin J, May Simera H, Lovett M, et al. A gradient of Bmp7 specifies the tonotopic axis in the developing inner ear. Nat Commun. 2014;5:3839 pubmed publisher
Tomlinson D, Knowles M. Altered splicing of FGFR1 is associated with high tumor grade and stage and leads to increased sensitivity to FGF1 in bladder cancer. Am J Pathol. 2010;177:2379-86 pubmed publisher
Yamamoto S, Fukumoto E, Yoshizaki K, Iwamoto T, Yamada A, Tanaka K, et al. Platelet-derived growth factor receptor regulates salivary gland morphogenesis via fibroblast growth factor expression. J Biol Chem. 2008;283:23139-49 pubmed publisher

product information

brand :

R&D Systems

master code :

1206-F3/CF

SKU :

1206-F3-025/CF

product name :

Recombinant Human FGF-3 Protein, CF

unit size :

25 ug

seo description :

The Recombinant Human FGF-3 Protein, CF from R&D Systems is derived from E. coli. The Recombinant Human FGF-3 Protein, CF has been validated for the following applications: Bioactivity.

target :

FGF-3

category :

Proteins and Enzymes

buffer :

Lyophilized from a 0.2 ╡m filtered solution in MOPS, Na2SO4, TCEP and EDTA.

conjugate :

Unconjugated

dilution :

Bioactivity

purity :

>97%, by SDS-PAGE under reducing conditions and visualized by silver stain.

species :

Human

theoretical molecular weight :

21.1 kDa

gene symbol :

FGF3

details of functionality :

Measured in a cell proliferation assay using NR6R-3T3 mouse fibroblast cells. Rizzino, A. et al . (1988) Cancer Res. 48 :4266; Thomas, K. et al . (1987) Methods Enzymol. 147 :120. The ED50 for this effect is 0.02-0.1 ╡g/mL in the presence of 1 ╡g/mL of heparin.

endotoxin note :

<0.10 EU per 1 ╡g of the protein by the LAL method.

accessionNumbers :

NP_005238

applications :

Bioactivity

source :

E. coli-derived Recombinant Human FGF-3 Protein, CF

USD :

480 USD

alt names :

FGF3, fibroblast growth factor 3, fibroblast growth factor 3 (murine mammary tumor virus integration site (v-int-2) oncogene homolog), HBGF-3, Hst, INT-2, mouse, oncogene INT2

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 3 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage