product summary
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company name :
R&D Systems
product type :
protein
product name :
Recombinant Human Cystatin D Protein, CF
catalog :
1202-PI-010
quantity :
10 ug
price :
432 USD
more info or order :
R&D Systems product webpage
citations: 3
Reference
Cheng T, Hitomi K, van Vlijmen Willems I, de Jongh G, Yamamoto K, Nishi K, et al. Cystatin M/E is a high affinity inhibitor of cathepsin V and cathepsin L by a reactive site that is distinct from the legumain-binding site. A novel clue for the role of cystatin M/E in epidermal cornification. J Biol Chem. 2006;281:15893-9 pubmed
Johnson G, Jiang W. Characterization of cathepsin L secreted by Sf21 insect cells. Arch Biochem Biophys. 2005;444:7-14 pubmed
Ito T, Komiya Ito A, Okuda K, Minaguchi K, Saitoh E, Yamada S, et al. Murine monoclonal antibody which can distinguish cystatins SA1 and SA2. Mol Immunol. 2005;42:1259-63 pubmed
product information
master code :
1202-PI
SKU :
1202-PI-010
product name :
Recombinant Human Cystatin D Protein, CF
unit size :
10 ug
description :
The Recombinant Human Cystatin D Protein, CF from R&D Systems is derived from NS0. The Recombinant Human Cystatin D Protein, CF has been validated for the following applications: Inhibition Activity.
target :
Cystatin D
category :
Proteins and Enzymes
buffer :
Lyophilized from a 0.2 ╡m filtered solution in MES and NaCl.
conjugate :
Unconjugated
purity :
>95%, by SDS-PAGE under reducing conditions and visualized by silver stain
species :
Human
observed molecular weight :
15 kDa, reducing conditions
theoretical molecular weight :
15 kDa
gene symbol :
CST5
details of functionality :
Measured by its ability to inhibit papain cleavage of a fluorogenic peptide substrate Z-FR-AMC (Catalog # ES009 ). The IC50 value is 8 nM, under the described conditions.
endotoxin note :
<1.0 EU per 1 ╡g of the protein by the LAL method.
accessionNumbers :
CAA49838
applications :
Inhibition Activity
source long :
Mouse myeloma cell line, NS0-derived human Cystatin D protein Thr29-Val142, with a C-terminal 10-His tag
source short :
NS0
USD :
432 USD
alt names :
CST5, CSTD, cystatin 5, cystatin D, Cystatin-5, cystatin-D, cysteine-proteinase inhibitor, MGC71922
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 6 months from date of receipt, -20 to -70 ░C as supplied. 3 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
R&D Systems product webpage
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.