Human PDGF Protein, CF | R&D Systems 120-HD-001 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

R&D Systems

product type :

protein

product name :

Human PDGF Protein, CF

catalog :

120-HD-001

quantity :

1 ug (also 5 ug)

price :

309 USD

citations: 18

Reference
Asega A, Menezes M, Trevisan Silva D, Cajado Carvalho D, Bertholim L, Oliveira A, et al. Cleavage of proteoglycans, plasma proteins and the platelet-derived growth factor receptor in the hemorrhagic process induced by snake venom metalloproteinases. Sci Rep. 2020;10:12912 pubmed publisher
Dihazi G, Eltoweissy M, Jahn O, Tampe B, Zeisberg M, Wülfrath H, et al. The Secretome Analysis of Activated Human Renal Fibroblasts Revealed Beneficial Effect of the Modulation of the Secreted Peptidyl-Prolyl Cis-Trans Isomerase A in Kidney Fibrosis. Cells. 2020;9: pubmed publisher
Krüger K, Schmid S, Paulsen F, Ignatius A, Klinger P, Hotfiel T, et al. Trefoil Factor 3 (TFF3) Is Involved in Cell Migration for Skeletal Repair. Int J Mol Sci. 2019;20: pubmed publisher
Kosanovic D, Platzek S, Petrović A, Sydykov A, Maripov A, Mamazhakypov A, et al. Circulating Apoptotic Signals During Acute and Chronic Exposure to High Altitude in Kyrgyz Population. Front Physiol. 2019;10:54 pubmed publisher
Ashraf S, Bell S, O Leary C, Canning P, Micu I, Fernandez J, et al. CAMKII as a therapeutic target for growth factor-induced retinal and choroidal neovascularization. JCI Insight. 2019;4: pubmed publisher
Liu J, Wang W, Wang L, Chen S, Tian B, Huang K, et al. IL-33 Initiates Vascular Remodelling in Hypoxic Pulmonary Hypertension by up-Regulating HIF-1α and VEGF Expression in Vascular Endothelial Cells. EBioMedicine. 2018;33:196-210 pubmed publisher
Meng M, Liu Y, Wang W, Wei C, Liu F, Du Z, et al. Umbilical cord mesenchymal stem cell transplantation in the treatment of multiple sclerosis. Am J Transl Res. 2018;10:212-223 pubmed
Guber S, Ebrahimian T, Heidari M, Eliopoulos N, Lehoux S. Endothelial nitric oxide synthase overexpressing human early outgrowth cells inhibit coronary artery smooth muscle cell migration through paracrine functions. Sci Rep. 2018;8:877 pubmed publisher
Lu C, Hsiao J, Liu H, Wu C. Characterization of an iron oxide nanoparticle labelling and MRI-based protocol for inducing human mesenchymal stem cells into neural-like cells. Sci Rep. 2017;7:3587 pubmed publisher
Murray L, Dunmore R, Camelo A, Da Silva C, Gustavsson M, Habiel D, et al. Acute cigarette smoke exposure activates apoptotic and inflammatory programs but a second stimulus is required to induce epithelial to mesenchymal transition in COPD epithelium. Respir Res. 2017;18:82 pubmed publisher
Tjomsland V, Sandnes D, Pomianowska E, Cizmovic S, Aasrum M, Brusevold I, et al. The TGFÎ²-SMAD3 pathway inhibits IL-1Î± induced interactions between human pancreatic stellate cells and pancreatic carcinoma cells and restricts cancer cell migration. J Exp Clin Cancer Res. 2016;35:122 pubmed publisher
Xie T, Liang J, Liu N, Huan C, Zhang Y, Liu W, et al. Transcription factor TBX4 regulates myofibroblast accumulation and lung fibrosis. J Clin Invest. 2016;126:3063-79 pubmed publisher
Raimondi C, Calleja V, Ferro R, Fantin A, Riley A, Potter B, et al. A Small Molecule Inhibitor of PDK1/PLCγ1 Interaction Blocks Breast and Melanoma Cancer Cell Invasion. Sci Rep. 2016;6:26142 pubmed publisher
Ballantyne M, Pinel K, Dakin R, Vesey A, Diver L, Mackenzie R, et al. Smooth Muscle Enriched Long Noncoding RNA (SMILR) Regulates Cell Proliferation. Circulation. 2016;133:2050-65 pubmed publisher
Johnson M, Mahoney J, Taroni J, Sargent J, Marmarelis E, Wu M, et al. Experimentally-derived fibroblast gene signatures identify molecular pathways associated with distinct subsets of systemic sclerosis patients in three independent cohorts. PLoS ONE. 2015;10:e0114017 pubmed publisher
Reading J, Yang J, Sabbah S, Skowera A, Knight R, Pinxteren J, et al. Clinical-grade multipotent adult progenitor cells durably control pathogenic T cell responses in human models of transplantation and autoimmunity. J Immunol. 2013;190:4542-52 pubmed publisher
Wilson T, Fridlyand J, Yan Y, Penuel E, Burton L, Chan E, et al. Widespread potential for growth-factor-driven resistance to anticancer kinase inhibitors. Nature. 2012;487:505-9 pubmed publisher
Gil J, Woo D, Shim J, Kim S, You H, Park S, et al. Vitronectin promotes oligodendrocyte differentiation during neurogenesis of human embryonic stem cells. FEBS Lett. 2009;583:561-7 pubmed publisher

product information

brand :

R&D Systems

master code :

120-HD

SKU :

120-HD-001

product name :

Human PDGF Protein, CF

description :

The Human PDGF Protein, CF from 120-HD-001 is derived from Human Platelets.

target :

PDGF

category :

Proteins and Enzymes

unit sizes :

1 ug (also 5 ug)

buffer :

Lyophilized from a 0.2 µm filtered solution in Acetonitrile and TFA.

conjugate :

Unconjugated

purity :

>97%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie® Blue Staining.

species :

Human

observed molecular weight :

Multiple bands between 28-31 kDa, non-reducing conditions

gene symbol :

PDGFA

details of functionality :

Measured in a cell proliferation assay using NR6R-3T3 mouse fibroblast cells. Raines, E.W. et al . (1985) Methods Enzymol. 109 :749. The ED50 for this effect is 1.5-6 ng/mL.

endotoxin note :

<0.10 EU per 1 µg of the protein by the LAL method.

applications :

Bioactivity

extended description :

Item is in-process of being discontinued

source :

Human Platelets

USD :

309 USD

product details :

Item is in-process of being discontinued

alt names :

PDGF1, PDGF-1, PDGFA, PDGF-A

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution.