This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
R&D Systems
product type :
protein
product name :
Recombinant Human TWEAK R/TNFRSF12 Fc Chimera Protein, CF
catalog :
1199-TW
quantity :
50 ug
price :
339 USD
citations: 1
Reference
Dhruv H, Loftus J, Narang P, Petit J, Fameree M, Burton J, et al. Structural basis and targeting of the interaction between fibroblast growth factor-inducible 14 and tumor necrosis factor-like weak inducer of apoptosis. J Biol Chem. 2013;288:32261-76 pubmed publisher
product information
brand :
R&D Systems
master code :
1199-TW
SKU :
1199-TW-050
product name :
Recombinant Human TWEAK R/TNFRSF12 Fc Chimera Protein, CF
description :
The Recombinant Human TWEAK R/TNFRSF12 Fc Chimera Protein, CF from R&D Systems is derived from NS0.
target :
TWEAK R/TNFRSF12
category :
Proteins and Enzymes
unit size :
50 ug
buffer :
Lyophilized from a 0.2 µm filtered solution in PBS.
conjugate :
Unconjugated
purity :
>90%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie® Blue Staining.
species :
Human
observed molecular weight :
35-45 kDa, reducing conditions
theoretical molecular weight :
32 kDa (monomer)
gene symbol :
TNFRSF12A
details of functionality :
Measured by its ability to inhibit the TWEAK-dependent proliferation of HUVEC human umbilical vein endothelial cells. The ED50 for this effect is 10-30 ng/mL in the presence of 15 ng/mL recombinant human TWEAK.
endotoxin note :
<0.10 EU per 1 µg of the protein by the LAL method.
catalog number base :
1199-TW
accessionNumbers :
Q9NP84
source :
Mouse myeloma cell line, NS0-derived human TWEAK R/TNFRSF12 protein Human TWEAK R (Glu28-Trp79) Accession # Q9NP84 IEGRMD Human IgG1 (Pro100-Lys330) N-terminus C-terminus
2020 USD :
339
2021 USD :
339 USD
alt names :
CD266, CD266 antigen, FGF-inducible 14, Fibroblast growth factor-inducible immediate-early response protein 14, Fn14, FN14tumor necrosis factor receptor superfamily member 12A, TNFRSF12, TNFRSF12A, tumor necrosis factor receptor superfamily, member 12A, TweakR, Tweak-receptor, type I transmembrane protein Fn14
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution.
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.