Recombinant Mouse TREM-1 Fc Chimera Protein, CF | R&D Systems 1187-TR-025 product information

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Mouse TREM-1 Fc Chimera Protein, CF

catalog :

1187-TR-025

quantity :

25 ug

price :

432 USD

more info or order :

R&D Systems product webpage

citations: 4

Reference
Denning N, Aziz M, Murao A, Gurien S, Ochani M, Prince J, et al. Extracellular CIRP as an endogenous TREM-1 ligand to fuel inflammation in sepsis. JCI Insight. 2020;5: pubmed publisher
Gao S, Yuan L, Wang Y, Hua C. Enhanced expression of TREM-1 in splenic cDCs in lupus prone mice and it was modulated by miRNA-150. Mol Immunol. 2017;81:127-134 pubmed publisher
Wu M, Peng A, Sun M, Deng Q, Hazlett L, Yuan J, et al. TREM-1 amplifies corneal inflammation after Pseudomonas aeruginosa infection by modulating Toll-like receptor signaling and Th1/Th2-type immune responses. Infect Immun. 2011;79:2709-16 pubmed publisher
Hsieh C, Koike M, Spusta S, Niemi E, Yenari M, Nakamura M, et al. A role for TREM2 ligands in the phagocytosis of apoptotic neuronal cells by microglia. J Neurochem. 2009;109:1144-56 pubmed publisher

product information

brand :

R&D Systems

master code :

1187-TR

SKU :

1187-TR-025

product name :

Recombinant Mouse TREM-1 Fc Chimera Protein, CF

unit size :

25 ug

seo description :

The Recombinant Mouse TREM-1 Fc Chimera Protein, CF from R&D Systems is derived from NS0. The Recombinant Mouse TREM-1 Fc Chimera Protein, CF has been validated for the following applications: Bioactivity.

target :

TREM-1

category :

Proteins and Enzymes

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS.

conjugate :

Unconjugated

dilution :

Bioactivity

purity :

>95%, by SDS-PAGE under reducing conditions and visualized by silver stain.

species :

Mouse

observed molecular weight :

60-73 kDa, reducing conditions

theoretical molecular weight :

47 kDa (monomer)

gene symbol :

Trem1

details of functionality :

Measured by its ability to block anti-TREM-1-induced TNF-alpha secretion by P388D1 mouse lymphoma cells. The ED50 for this effect is 2-8 ng/mL in the presence of 0.5-2 ╡g/mL of Goat Anti-Mouse TREM-1 (Catalog # AF1187 ).

endotoxin note :

<0.10 EU per 1 ╡g of the protein by the LAL method.

accessionNumbers :

Q9JKE2

applications :

Bioactivity

source :

NS0-derived Recombinant Mouse TREM-1 Fc Chimera Protein, CF

USD :

432 USD

alt names :

CD354, CD354 antigen, TREM1, TREM-1Triggering receptor expressed on monocytes 1, triggering receptor expressed on myeloid cells 1, triggering-receptor TREM1

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 3 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage