Recombinant Human Serpin F1/PEDF Protein, CF | R&D Systems 1177-SF-025 product information

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Human Serpin F1/PEDF Protein, CF

catalog :

1177-SF-025

quantity :

25 ug

price :

432 USD

more info or order :

R&D Systems product webpage

citations: 4

Reference
Beer M, Kuhrt H, Kohen L, Wiedemann P, Bringmann A, Hollborn M. Kir4.2 Potassium Channels in Retinal Pigment Epithelial Cells In Vitro: Contribution to Cell Viability and Proliferation, and Down-Regulation by Vascular Endothelial Growth Factor. Biomolecules. 2022;12: pubmed publisher
Messerschmidt L, Fischer S, Wiedemann P, Bringmann A, Hollborn M. Osmotic induction of cyclooxygenase-2 in RPE cells: Stimulation of inflammasome activation. Mol Vis. 2019;25:329-344 pubmed
Eichler W, Savković Cvijić H, Burger S, Beck M, Schmidt M, Wiedemann P, et al. Müller Cell-Derived PEDF Mediates Neuroprotection via STAT3 Activation. Cell Physiol Biochem. 2017;44:1411-1424 pubmed publisher
Tucker B, Anfinson K, Mullins R, Stone E, Young M. Use of a synthetic xeno-free culture substrate for induced pluripotent stem cell induction and retinal differentiation. Stem Cells Transl Med. 2013;2:16-24 pubmed publisher

product information

brand :

R&D Systems

master code :

1177-SF

SKU :

1177-SF-025

product name :

Recombinant Human Serpin F1/PEDF Protein, CF

unit size :

25 ug

seo description :

The Recombinant Human Serpin F1/PEDF Protein, CF from R&D Systems is derived from NS0. The Recombinant Human Serpin F1/PEDF Protein, CF has been validated for the following applications: Bioactivity.

target :

Serpin F1/PEDF

category :

Proteins and Enzymes

buffer :

Lyophilized from a 0.2 ╡m filtered solution in Tris and NaCl.

conjugate :

Unconjugated

dilution :

Bioactivity

purity :

>95%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie« Blue Staining.

species :

Human

observed molecular weight :

45-53 kDa, reducing conditions

theoretical molecular weight :

45 kDa

gene symbol :

SERPINF1

details of functionality :

Measured by its ability to enhance the adhesion of Saos-2 human osteosarcoma cells to bovine Collagen I coated plate. Eth, E.K. et al . (2007) Cancer Gene Therapy. 14 :616. The ED50 for this effect is 0.15-0.75 ╡g/mL.

endotoxin note :

<1.0 EU per 1 ╡g of the protein by the LAL method.

accessionNumbers :

AAK92491

applications :

Bioactivity

source :

NS0-derived Recombinant Human Serpin F1/PEDF Protein, CF

USD :

432 USD

alt names :

Cell proliferation-inducing gene 35 protein, EPC-1, EPC-1PIG35, PEDF, PEDFpigment epithelium-derived factor, pigment epithelium derived factor), member 1, proliferation-inducing protein 35, serine (or cysteine) proteinase inhibitor, clade F (alpha-2 antiplasmin, Serpin F1, serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epitheliumderived factor), member 1

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 3 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage