Recombinant Mouse ICAM-5 Fc Chimera Protein, CF | R&D Systems 1173-M5 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Mouse ICAM-5 Fc Chimera Protein, CF

catalog :

1173-M5

quantity :

50 ug

price :

339 USD

citations: 5

Reference
Paetau S, Rolova T, Ning L, Gahmberg C. Neuronal ICAM-5 Inhibits Microglia Adhesion and Phagocytosis and Promotes an Anti-inflammatory Response in LPS Stimulated Microglia. Front Mol Neurosci. 2017;10:431 pubmed publisher
Furutani Y, Kawasaki M, Matsuno H, Mitsui S, Mori K, Yoshihara Y. Vitronectin induces phosphorylation of ezrin/radixin/moesin actin-binding proteins through binding to its novel neuronal receptor telencephalin. J Biol Chem. 2012;287:39041-9 pubmed publisher
Niedringhaus M, Chen X, Dzakpasu R, Conant K. MMPs and soluble ICAM-5 increase neuronal excitability within in vitro networks of hippocampal neurons. PLoS ONE. 2012;7:e42631 pubmed publisher
Conant K, Lonskaya I, Szklarczyk A, Krall C, Steiner J, Maguire Zeiss K, et al. Methamphetamine-associated cleavage of the synaptic adhesion molecule intercellular adhesion molecule-5. J Neurochem. 2011;118:521-32 pubmed publisher
Conant K, Wang Y, Szklarczyk A, Dudak A, Mattson M, Lim S. Matrix metalloproteinase-dependent shedding of intercellular adhesion molecule-5 occurs with long-term potentiation. Neuroscience. 2010;166:508-21 pubmed publisher

product information

brand :

R&D Systems

master code :

1173-M5

SKU :

1173-M5-050

product name :

Recombinant Mouse ICAM-5 Fc Chimera Protein, CF

description :

The Recombinant Mouse ICAM-5 Fc Chimera Protein, CF from R&D Systems is derived from NS0. The Recombinant Mouse ICAM-5 Fc Chimera Protein, CF has been validated for the following applications: Bioactivity.

target :

ICAM-5

category :

Proteins and Enzymes

unit size :

50 ug

buffer :

Lyophilized from a 0.2 µm filtered solution in Tris-Citrate and NaCl.

conjugate :

Unconjugated

purity :

>90%, by SDS-PAGE under reducing conditions and visualized by silver stain.

species :

Mouse

observed molecular weight :

166 kDa, reducing conditions

theoretical molecular weight :

112 kDa (monomer)

gene symbol :

Icam5

details of functionality :

Measured by the ability of the immobilized protein to support the adhesion of PMA-stimulated HSB2 human peripheral blood acute lymphoblastic leukemia cells. When 5 x 104 cells/well are added to recombinant mouse ICAM-5 Fc Chimera coated plates (25 µg/mL with 100 µL/well), 25% cells will adhere after 1 hour incubation at 37 °C. Optimal dilutions should be determined by each laboratory for each application.

endotoxin note :

<0.10 EU per 1 µg of the protein by the LAL method.

catalog number base :

1173-M5

accessionNumbers :

Q60625.1

applications :

Bioactivity

source :

Mouse myeloma cell line, NS0-derived mouse ICAM-5 protein Mouse ICAM-5 Leu31-Arg828 (Pro47Arg) Accession # Q60625.1 IEGRMD Human IgG1 (Pro100-Lys330) N-terminus C-terminus

2020 USD :

339

2021 USD :

339 USD

alt names :

ICAM5, ICAM-5, intercellular adhesion molecule 5, intercellular adhesion molecule 5, telencephalin, Telencephalin, TLCNTelencephalin, TLNtelencephalin

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution.