Recombinant Human Ret His-tag Protein | R&D Systems 1168-CR product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Human Ret His-tag Protein

catalog :

1168-CR

quantity :

50 ug

price :

339 USD

citations: 3

Reference
Chu Y, Bartus R, Manfredsson F, Olanow C, Kordower J. Long-term post-mortem studies following neurturin gene therapy in patients with advanced Parkinson's disease. Brain. 2020;143:960-975 pubmed publisher
Rosti K, Goldman A, Kajander T. Solution structure and biophysical characterization of the multifaceted signalling effector protein growth arrest specific-1. BMC Biochem. 2015;16:8 pubmed publisher
Lu B, PereiraPerrin M. A novel immunoprecipitation strategy identifies a unique functional mimic of the glial cell line-derived neurotrophic factor family ligands in the pathogen Trypanosoma cruzi. Infect Immun. 2008;76:3530-8 pubmed publisher

product information

brand :

R&D Systems

master code :

1168-CR

SKU :

1168-CR-050

product name :

Recombinant Human Ret His-tag Protein

description :

The Recombinant Human Ret His-tag Protein from R&D Systems is derived from Sf 21 (stably transfected). The Recombinant Human Ret His-tag Protein has been validated for the following applications: Binding Activity.

target :

Ret

category :

Proteins and Enzymes

unit size :

50 ug

buffer :

Lyophilized from a 0.2 µm filtered solution in PBS with BSA as a carrier protein.

conjugate :

Unconjugated

main entrez gene id :

5979

purity :

>90%, by SDS-PAGE under reducing conditions and visualized by silver stain.

species :

Human

observed molecular weight :

90 kDa, reducing conditions

theoretical molecular weight :

69 kDa

gene symbol :

RET

details of functionality :

Measured by its binding ability in a functional ELISA. When Recombinant Human Ret His-tag is immobilized at 1 µg/mL (100 µL/well), Recombinant Human GDNF (Catalog # 212-GD ) binds with an ED50 of 0.05-0.3 µg/mL in the presence of Recombinant Human GFR alpha-1/GDNF R alpha-1 Fc Chimera (Catalog # 714-GR ).

endotoxin note :

<0.10 EU per 1 µg of the protein by the LAL method.

catalog number base :

1168-CR

accessionNumbers :

P07949

applications :

Binding Activity

source :

extended description :

This product is in the process of being discontinued.

USD :

339 USD

alt names :

CDHF12MTC1, CDHR16, EC 2.7.10, Hirschsprung disease 1, Hirschsprung disease), MEN2A, MEN2B, multiple endocrine neoplasia and medullary thyroid carcinoma 1, ret proto-oncogene, RET transforming sequence

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution.