Recombinant Human Prolactin R Fc Chimera Protein, CF | R&D Systems 1167-PR-050 product information

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Human Prolactin R Fc Chimera Protein, CF

catalog :

1167-PR-050

quantity :

50 ug

price :

456 USD

more info or order :

R&D Systems product webpage

citations: 1

Reference
Basu R, Brody R, Sandbhor U, Kulkarni P, Davis E, Swegan D, et al. Structure and function of a dual antagonist of the human growth hormone and prolactin receptors with site-specific PEG conjugates. J Biol Chem. 2023;299:105030 pubmed publisher

product information

master code :

1167-PR

SKU :

1167-PR-050

product name :

Recombinant Human Prolactin R Fc Chimera Protein, CF

unit size :

50 ug

description :

The Recombinant Human Prolactin R Fc Chimera Protein, CF from R&D Systems is derived from NS0. The Recombinant Human Prolactin R Fc Chimera Protein, CF has been validated for the following applications: Bioactivity.

target :

Prolactin R

category :

Proteins and Enzymes

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS.

conjugate :

Unconjugated

purity :

>90%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie« Blue Staining.

species :

Human

observed molecular weight :

66 kDa, reducing conditions

theoretical molecular weight :

51 kDa (monomer)

gene symbol :

PRLR

details of functionality :

Measured by its ability to inhibit Prolactin-induced proliferation of Nb2-11 rat lymphoma cells. Gout, P.W. et al . (1980) Cancer Res. 40 :2433. The ED50 of this effect is 0.04-0.24 ╡g/mL in the presence of 0.5 ng/mL of recombinant human Prolactin.

endotoxin note :

<0.10 EU per 1 ╡g of the protein by the LAL method.

accessionNumbers :

P16471

applications :

Bioactivity

source long :

Mouse myeloma cell line, NS0-derived human Prolactin R protein Human Prolactin R (Gln25-Asp234) Accession # P16471 IEGRMD Human IgG1 (Pro100-Lys330) N-terminus C-terminus

source short :

NS0

USD :

456 USD

alt names :

delta 4-delta 7/11 truncated prolactin receptor, delta 4-SF1b truncated prolactin receptor, hPRL receptor, hPRLrI, PRLR, PRL-R, prolactin receptor, prolactin receptor delta 7/11, ProlactinR, secreted prolactin binding protein

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 3 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage