Recombinant Human Bcl-2 related protein A1 (aa 1-152), CF | R&D Systems 1160-A1-050 product information

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Human Bcl-2 related protein A1 (aa 1-152), CF

catalog :

1160-A1-050

quantity :

50 ug

price :

432 USD

more info or order :

R&D Systems product webpage

citations: 2

Reference
Li R, Ding C, Zhang J, Xie M, Park D, Ding Y, et al. Modulation of Bax and mTOR for Cancer Therapeutics. Cancer Res. 2017;77:3001-3012 pubmed publisher
Iwata A, De Claro R, Morgan Stevenson V, Tupper J, Schwartz B, Liu L, et al. Extracellular administration of BCL2 protein reduces apoptosis and improves survival in a murine model of sepsis. PLoS ONE. 2011;6:e14729 pubmed publisher

product information

master code :

1160-A1

SKU :

1160-A1-050

product name :

Recombinant Human Bcl-2 related protein A1 (aa 1-152), CF

unit size :

50 ug

description :

The Recombinant Human Bcl-2 related protein A1 (aa 1-152), CF from R&D Systems is derived from E. coli. The Recombinant Human Bcl-2 related protein A1 (aa 1-152), CF has been validated for the following applications: Inhibition Activity.

target :

Bcl-2 related protein A1

category :

Proteins and Enzymes

buffer :

Supplied as a 0.2 ╡m filtered solution in NaH2PO4, NaCl and Glycerol.

conjugate :

Unconjugated

purity :

>95%, by SDS-PAGE under reducing conditions and visualized by silver stain

species :

Human

observed molecular weight :

16 kDa, non-reducing conditions

theoretical molecular weight :

18 kDa

gene symbol :

BCL2A1

details of functionality :

Measured by its ability to inhibit Caspase-8-cleaved BID-mediated release of cytochromeác from isolated mouse liver mitochondria using the Rat/Mouse Cytochrome c Quantikine ELISA (Catalog # MCTC0 ) to quantify cytochromeác. The typical EC50 for human Bcl-2 related protein A1 Minus C-terminus in this assay is 15-200 nM.

endotoxin note :

<1.0 EU per 1 ╡g of the protein by the LAL method.

accessionNumbers :

Q16548

applications :

Inhibition Activity

source long :

E. coli -derived human Bcl-2 related protein A1 protein Thr2-Ser152, with a C-terminal 6-His tag

source short :

E. coli

USD :

432 USD

alt names :

ACC-1, ACC-2, BCL2A1, Bcl2L5, Bcl2-L-5, BCL2L5HBPA1, Bcl-2-like protein 5, BCL2-related protein A1, Bfl-1, BFL1bcl-2-related protein A1, GRS, GRSbcl2-L-5, hematopoietic BCL2-related protein A1, Hemopoietic-specific early response protein, Protein BFL-1, Protein GRS

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 6 months from date of receipt, -20 to -70 ░C as supplied. 3 months, -20 to -70 ░C under sterile conditions after opening.

more info or order :

R&D Systems product webpage