Recombinant Mouse NGFR/TNFRSF16 Fc Chimera Protein, CF | R&D Systems 1157-NR-050 product information

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Mouse NGFR/TNFRSF16 Fc Chimera Protein, CF

catalog :

1157-NR-050

quantity :

50 ug

price :

432 USD

more info or order :

R&D Systems product webpage

citations: 3

Reference
Shepheard S, Chataway T, Schultz D, Rush R, Rogers M. The extracellular domain of neurotrophin receptor p75 as a candidate biomarker for amyotrophic lateral sclerosis. PLoS ONE. 2014;9:e87398 pubmed publisher
Hasebe N, Fujita Y, Ueno M, Yoshimura K, Fujino Y, Yamashita T. Soluble ?-amyloid Precursor Protein Alpha binds to p75 neurotrophin receptor to promote neurite outgrowth. PLoS ONE. 2013;8:e82321 pubmed publisher
Vaegter C, Jansen P, Fjorback A, Glerup S, Skeldal S, Kjolby M, et al. Sortilin associates with Trk receptors to enhance anterograde transport and neurotrophin signaling. Nat Neurosci. 2011;14:54-61 pubmed publisher

product information

master code :

1157-NR

SKU :

1157-NR-050

product name :

Recombinant Mouse NGFR/TNFRSF16 Fc Chimera Protein, CF

unit size :

50 ug

description :

The Recombinant Mouse NGFR/TNFRSF16 Fc Chimera Protein, CF from R&D Systems is derived from NS0. The Recombinant Mouse NGFR/TNFRSF16 Fc Chimera Protein, CF has been validated for the following applications: Bioactivity.

target :

NGFR/TNFRSF16

category :

Proteins and Enzymes

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS.

conjugate :

Unconjugated

purity :

>90%, by SDS-PAGE under reducing conditions and visualized by silver stain.

species :

Mouse

observed molecular weight :

75-100 kDa, reducing conditions

theoretical molecular weight :

50.4 kDa (monomer)

gene symbol :

Ngfr

details of functionality :

Measured by its ability to inhibit ▀-NGF-dependent proliferation of TF-1 human erythroleukemic cells. Kitamura, T. et al . (1989) J. Cell Physiol. 140 :323. The ED50 for this effect is 0.5-1.5 ╡g/mL in the presence of 2 ng/mL of rm▀-NGF.

endotoxin note :

<0.10 EU per 1 ╡g of the protein by the LAL method.

accessionNumbers :

Q9Z0W1.1

applications :

Bioactivity

source long :

Mouse myeloma cell line, NS0-derived mouse NGFR/TNFRSF16 protein Mouse NGF R (Gly20 - Asn243) Accession # Q9Z0W1.1 DIEGRMD Human IgG1 (Pro100 - Lys330) N-terminus C-terminus

source short :

NS0

USD :

432 USD

alt names :

CD271, CD271 antigen, Gp80-LNGFR, member 16, nerve growth factor receptor, NGF R, NGF receptor, p75 ICD, p75 NTR, TNFRSF16, TNFRSF16nerve growth factor receptor (TNFR superfamily, member 16), tumor necrosis factor receptor superfamily member 16

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 3 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage