product summary
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company name :
R&D Systems
product type :
protein
product name :
Recombinant Human Galectin-3 Protein, CF
catalog :
1154-GA-050/CF
quantity :
50 ug
price :
400 USD
more info or order :
R&D Systems product webpage
citations: 9
Reference
Freitag N, Tirado Gonzalez I, Barrientos G, Powell K, Boehm Sturm P, Koch S, et al. Galectin-3 deficiency in pregnancy increases the risk of fetal growth restriction (FGR) via placental insufficiency. Cell Death Dis. 2020;11:560 pubmed publisher
Terävä J, Tiainen L, Lamminmaki U, Kellokumpu Lehtinen P, Pettersson K, Gidwani K. Lectin nanoparticle assays for detecting breast cancer-associated glycovariants of cancer antigen 15-3 (CA15-3) in human plasma. PLoS ONE. 2019;14:e0219480 pubmed publisher
Ibarrola J, Sadaba R, García Peña A, Arrieta V, Martínez Martínez E, Alvarez V, et al. A role for fumarate hydratase in mediating oxidative effects of galectin-3 in human cardiac fibroblasts. Int J Cardiol. 2018;258:217-223 pubmed publisher
Seguin L, Camargo M, Wettersten H, Kato S, Desgrosellier J, von Schalscha T, et al. Galectin-3, a Druggable Vulnerability for KRAS-Addicted Cancers. Cancer Discov. 2017;7:1464-1479 pubmed publisher
Zhao J, Shiratori B, Chagan Yasutan H, Matsumoto M, Niki T, Tanaka M, et al. Secretion of IFN-γ Associated with Galectin-9 Production by Pleural Fluid Cells from a Patient with Extrapulmonary Tuberculosis. Int J Mol Sci. 2017;18: pubmed publisher
Mattsson J, Ravela S, Hekim C, Jonsson M, Malm J, Närvänen A, et al. Proteolytic activity of prostate-specific antigen (PSA) towards protein substrates and effect of peptides stimulating PSA activity. PLoS ONE. 2014;9:e107819 pubmed publisher
Mackinnon A, Liu X, Hadoke P, Miller M, Newby D, Sethi T. Inhibition of galectin-3 reduces atherosclerosis in apolipoprotein E-deficient mice. Glycobiology. 2013;23:654-63 pubmed publisher
Debierre Grockiego F, Niehus S, Coddeville B, Elass E, Poirier F, Weingart R, et al. Binding of Toxoplasma gondii glycosylphosphatidylinositols to galectin-3 is required for their recognition by macrophages. J Biol Chem. 2010;285:32744-50 pubmed publisher
Papaspyridonos M, McNeill E, de Bono J, Smith A, Burnand K, Channon K, et al. Galectin-3 is an amplifier of inflammation in atherosclerotic plaque progression through macrophage activation and monocyte chemoattraction. Arterioscler Thromb Vasc Biol. 2008;28:433-40 pubmed
product information
brand :
R&D Systems
master code :
1154-GA/CF
SKU :
1154-GA-050/CF
product name :
Recombinant Human Galectin-3 Protein, CF
unit size :
50 ug
seo description :
The Recombinant Human Galectin-3 Protein, CF from R&D Systems is derived from E. coli. The Recombinant Human Galectin-3 Protein, CF has been validated for the following applications: Bioactivity.
target :
Galectin-3
category :
Proteins and Enzymes
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS and Betamercaptoethanol.
conjugate :
Unconjugated
dilution :
Bioactivity
purity :
>90%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie« Blue Staining.
species :
Human
theoretical molecular weight :
26 kDa
gene symbol :
LGALS3
details of functionality :
Measured by its ability to agglutinate human red blood cells. Hadari, Y.R. et al . (2000) J. Cell Sci. 113 :2385. The ED50 for this effect is 3-10á╡g/mL.
endotoxin note :
<0.01 EU per 1 ╡g of the protein by the LAL method.
top caption :
Recombinant Human Galectin-3 Protein Bioactivity
accessionNumbers :
P17931
applications :
Bioactivity
source :
E. coli-derived Recombinant Human Galectin-3 Protein, CF
extended description :
A New rh Galectin-3 is Now Available! Improved activity and purity; Mammalian cell expressed!
USD :
400 USD
product details :
A New rh Galectin-3 is Now Available! Improved activity and purity; Mammalian cell expressed!
alt names :
AGE-R3, Carbohydrate-binding protein 35, CBP 35,35 kDa lectin, CBP35, Gal-3, GAL3, galactin-3, Galactose-specific lectin 3, Galactoside-binding protein, GALBPCBP35, galectin-3, Galectin3, GALIG, IgE-binding protein, L29, L31, L-31, Laminin-binding protein, Lectin L-29, lectin, galactoside-binding, soluble, 3, LGALS2, LGALS3, Mac-2, Mac-2 antigen, MAC2GAL3
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 3 months, 2 to 8 ░C under sterile conditions after reconstitution.
more info or order :
R&D Systems product webpage
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.