Recombinant Human CLF-1/CLC Complex Protein | R&D Systems 1151-CL-025 product information

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Human CLF-1/CLC Complex Protein

catalog :

1151-CL-025

quantity :

25 ug

price :

432 USD

more info or order :

R&D Systems product webpage

citations: 3

Reference
KASS D, Yu G, Loh K, Savir A, Borczuk A, Kahloon R, et al. Cytokine-like factor 1 gene expression is enriched in idiopathic pulmonary fibrosis and drives the accumulation of CD4+ T cells in murine lungs: evidence for an antifibrotic role in bleomycin injury. Am J Pathol. 2012;180:1963-78 pubmed publisher
Larsen J, Hansen M, Møller B, Madsen P, Scheller J, Nielsen M, et al. Sortilin facilitates signaling of ciliary neurotrophic factor and related helical type 1 cytokines targeting the gp130/leukemia inhibitory factor receptor beta heterodimer. Mol Cell Biol. 2010;30:4175-87 pubmed publisher
Schmidt Ott K, Yang J, Chen X, Wang H, Paragas N, Mori K, et al. Novel regulators of kidney development from the tips of the ureteric bud. J Am Soc Nephrol. 2005;16:1993-2002 pubmed

product information

brand :

R&D Systems

master code :

1151-CL

SKU :

1151-CL-025

product name :

Recombinant Human CLF-1/CLC Complex Protein

unit size :

25 ug

seo description :

The Recombinant Human CLF-1/CLC Complex Protein from R&D Systems is derived from NS0. The Recombinant Human CLF-1/CLC Complex Protein has been validated for the following applications: Bioactivity.

target :

CLF-1/CLC Complex

category :

Proteins and Enzymes

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS with BSA as a carrier protein.

conjugate :

Unconjugated

dilution :

Bioactivity

purity :

>85%, by SDS-PAGE under reducing conditions and visualized by silver stain

species :

Human

observed molecular weight :

50-65 kDa (CLF-1) 28-30 kDa (CLC), reducing conditions

theoretical molecular weight :

44.5 kDa (CLF-1) 23 kDa (CLC)

gene symbol :

CRLF1

details of functionality :

Measured in a cell proliferation assay using TF-1 human erythroleukemic cells transfected with human CNTF R alpha . The ED50 for this effect is 0.5-3.5 ng/mL.

endotoxin note :

<0.10 EU per 1 ╡g of the protein by the LAL method.

accessionNumbers :

O75462 (CLF-1) Q9UBD9 (CLC)

applications :

Bioactivity

source :

NS0-derived Recombinant Human CLF-1/CLC Complex Protein

USD :

432 USD

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 3 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage