Recombinant Human BMP-3 Protein, CF | R&D Systems 113-BP-100/CF product information

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Human BMP-3 Protein, CF

catalog :

113-BP-100/CF

quantity :

100 ug

price :

493 USD

more info or order :

R&D Systems product webpage

citations: 5

Reference
Platko K, Gyulay G, Lebeau P, Macdonald M, Lynn E, Byun J, et al. GDF10 is a negative regulator of vascular calcification. J Biol Chem. 2024;300:107805 pubmed publisher
Castonguay R, Werner E, Matthews R, Presman E, Mulivor A, Solban N, et al. Soluble endoglin specifically binds bone morphogenetic proteins 9 and 10 via its orphan domain, inhibits blood vessel formation, and suppresses tumor growth. J Biol Chem. 2011;286:30034-46 pubmed publisher
Stewart A, Guan H, Yang K. BMP-3 promotes mesenchymal stem cell proliferation through the TGF-beta/activin signaling pathway. J Cell Physiol. 2010;223:658-66 pubmed publisher
Tseng Y, Kokkotou E, Schulz T, Huang T, Winnay J, Taniguchi C, et al. New role of bone morphogenetic protein 7 in brown adipogenesis and energy expenditure. Nature. 2008;454:1000-4 pubmed publisher
Mogi K, Goto M, Ohno E, Azumi Y, Takeuchi S, Toyoizumi R. Xenopus neurula left-right asymmetry is respeficied by microinjecting TGF-beta5 protein. Int J Dev Biol. 2003;47:15-29 pubmed

product information

brand :

R&D Systems

master code :

113-BP/CF

SKU :

113-BP-100/CF

product name :

Recombinant Human BMP-3 Protein, CF

unit size :

100 ug

seo description :

The Recombinant Human BMP-3 Protein, CF from R&D Systems is derived from E. coli. The Recombinant Human BMP-3 Protein, CF has been validated for the following applications: Bioactivity.

target :

BMP-3

category :

Proteins and Enzymes

buffer :

Lyophilized from a 0.2 ╡m filtered solution in Acetonitrile and TFA.

conjugate :

Unconjugated

dilution :

Bioactivity

purity :

>95%, by SDS-PAGE under reducing conditions and visualized by silver stain

species :

Human

theoretical molecular weight :

12.5 kDa (monomer)

gene symbol :

BMP3

details of functionality :

Measured by its ability to inhibit BMP-2-induced activity in MC3T3-E1 mouse preosteoblast cells. Daluiski, A. et al . (2001) Nature Genetics 27 :84. 30á╡g/mL of hBMP-3 will antagonize hBMP-2 (0.25 ╡g/mL) induction of alkaline phosphatase in MC3T3E1 cells by 50%.

endotoxin note :

<0.10 EU per 1 ╡g of the protein by the LAL method.

accessionNumbers :

P12645.1

applications :

Bioactivity

source :

E. coli-derived Recombinant Human BMP-3 Protein, CF

USD :

493 USD

alt names :

BMP3, BMP-3, BMP3A, BMP-3A, bone morphogenetic protein 3, bone morphogenetic protein 3 (osteogenic), Bone morphogenetic protein 3A, bone morphogenetic protein-3, osteogenin

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 3 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage