Recombinant Mouse TRAIL/TNFSF10 Protein | R&D Systems 1121-TL-010 product information

product summary

company name :

R&D Systems

product type :

protein

product name :

Recombinant Mouse TRAIL/TNFSF10 Protein

catalog :

1121-TL-010

quantity :

10 ug

price :

432 USD

more info or order :

R&D Systems product webpage

citations: 8

Reference
May L, Hu B, Jerajani P, Jagdeesh A, Alhawiti O, Cai L, et al. The Innate Immune System and the TRAIL-Bcl-XL Axis Mediate a Sex Bias in Lung Cancer and Confer a Therapeutic Vulnerability in Females. Cancer Res. 2024;84:4140-4155 pubmed publisher
Tian S, Liu D, Wang D, Ren F, Xia P. Aldehyde Dehydrogenase 1 (ALDH1) Promotes the Toxicity of TRAIL in Non-Small Cell Lung Cancer Cells via Post-Transcriptional Regulation of MEK-1 Expression. Cell Physiol Biochem. 2018;51:217-227 pubmed publisher
Su T, Bondar T, Zhou X, Zhang C, He H, Medzhitov R. Two-signal requirement for growth-promoting function of Yap in hepatocytes. elife. 2015;4: pubmed publisher
Kichev A, Rousset C, Baburamani A, Levison S, Wood T, Gressens P, et al. Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) signaling and cell death in the immature central nervous system after hypoxia-ischemia and inflammation. J Biol Chem. 2014;289:9430-9 pubmed publisher
Starkey M, Nguyen D, Essilfie A, Kim R, Hatchwell L, Collison A, et al. Tumor necrosis factor-related apoptosis-inducing ligand translates neonatal respiratory infection into chronic lung disease. Mucosal Immunol. 2014;7:478-88 pubmed publisher
Freeman B, Hammarlund E, Raué H, Slifka M. Regulation of innate CD8+ T-cell activation mediated by cytokines. Proc Natl Acad Sci U S A. 2012;109:9971-6 pubmed publisher
Kayamuro H, Yoshioka Y, Abe Y, Katayama K, Yoshida T, Yamashita K, et al. TNF superfamily member, TL1A, is a potential mucosal vaccine adjuvant. Biochem Biophys Res Commun. 2009;384:296-300 pubmed publisher
Dumitru C, Carpinteiro A, Trarbach T, Hengge U, Gulbins E. Doxorubicin enhances TRAIL-induced cell death via ceramide-enriched membrane platforms. Apoptosis. 2007;12:1533-41 pubmed

product information

brand :

R&D Systems

master code :

1121-TL

SKU :

1121-TL-010

product name :

Recombinant Mouse TRAIL/TNFSF10 Protein

unit size :

10 ug

seo description :

The Recombinant Mouse TRAIL/TNFSF10 Protein from R&D Systems is derived from E. coli. The Recombinant Mouse TRAIL/TNFSF10 Protein has been validated for the following applications: Bioactivity.

target :

TRAIL/TNFSF10

category :

Proteins and Enzymes

buffer :

Lyophilized from a 0.2 ╡m filtered solution in Tris, Ammonium Sulfate and ZnSO4 with Trehalose and with BSA as a carrier protein.

conjugate :

Unconjugated

dilution :

Bioactivity

purity :

>95%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie« Blue Staining.

species :

Mouse

theoretical molecular weight :

20 kda

gene symbol :

Tnfsf10

details of functionality :

Measured in a cytotoxicity assay using L-929 mouse fibroblast cells in the presence of the metabolic inhibitor actinomycináD. Matthews,áN. and M.L. Neale (1987) in Lymphokines and Interferons, A Practical Approach. Clemens, M.J. et al . (eds): IRL Press. 221. The ED50 for this effect is 0.2-1.2 ng/mL.

endotoxin note :

<0.01 EU per 1 ╡g of the protein by the LAL method.

accessionNumbers :

P50592

applications :

Bioactivity

source :

E. coli-derived Recombinant Mouse TRAIL/TNFSF10 Protein

USD :

432 USD

alt names :

Apo-2 ligand, APO2L, Apo-2Ltumor necrosis factor (ligand) family, member 10, APO2Ltumor necrosis factor apoptosis-inducing ligand splice variant delta, CD253, CD253 antigen, Protein TRAIL, TL2, TNF-related apoptosis-inducing ligand, TNFSF10, TRAILTNF-related apoptosis inducing ligand TRAIL, tumor necrosis factor (ligand) superfamily, member 10, tumor necrosis factor ligand superfamily member 10

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 3 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage