product summary
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company name :
R&D Systems
product type :
protein
product name :
Recombinant Mouse Frizzled-1 Fc Chimera Protein, CF
catalog :
1120-FZ-050
quantity :
50 ug
price :
498 USD
more info or order :
citations: 2
Reference
Ramirez V, Ramos Fernández E, Henriquez J, Lorenzo A, Inestrosa N. Wnt-5a/Frizzled9 Receptor Signaling through the G?o-G?? Complex Regulates Dendritic Spine Formation. J Biol Chem. 2016;291:19092-107 pubmed publisher
Lindsley R, Gill J, Kyba M, Murphy T, Murphy K. Canonical Wnt signaling is required for development of embryonic stem cell-derived mesoderm. Development. 2006;133:3787-96 pubmed
product information
master code :
1120-FZ
SKU :
1120-FZ-050
product name :
Recombinant Mouse Frizzled-1 Fc Chimera Protein, CF
unit size :
50 ug
description :
The Recombinant Mouse Frizzled-1 Fc Chimera Protein, CF from R&D Systems is derived from NS0. The Recombinant Mouse Frizzled-1 Fc Chimera Protein, CF has been validated for the following applications: Binding Activity.
target :
Frizzled-1
category :
Proteins and Enzymes
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS.
conjugate :
Unconjugated
purity :
>95%, by SDS-PAGE under reducing conditions and visualized by silver stain
species :
Mouse
observed molecular weight :
55-62 kDa, reducing conditions
theoretical molecular weight :
46 kDa (monomer)
gene symbol :
Fzd1
details of functionality :
Measured by its ability to bind biotinylated Wnt-3a in a functional ELISA with an estimated KDá á10ánM.
endotoxin note :
<0.10 EU per 1 ╡g of the protein by the LAL method.
accessionNumbers :
O70421
applications :
Binding Activity
source long :
Mouse myeloma cell line, NS0-derived mouse Frizzled-1 protein Mouse Frizzled-1 (Gln72 - His248) with substitution Met122Ile. Accession # O70421 IEGRMD Human IgG1 (Pro100 - Lys330) N-terminus C-terminus
source short :
NS0
USD :
498 USD
alt names :
DKFZp564G072, FLJ95923, frizzled family receptor 1, frizzled homolog 1, frizzled, Drosophila, homolog of, 1, frizzled-1, Frizzled1, fz-1, FZD1, fzE1, hFz1, seven transmembrane spanning receptor, Wnt receptor
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 3 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.